1 Result for "

COX-2-IN-48

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "COX-2-IN-48" in MCE Product Catalog:

Cat. No.: HY-168070
Target:  

COX NF-κB NO Synthase

Research Areas:  

Inflammation/Immunology

COX-2-IN-48 (5-25), a COX-2 inhibitor with an IC50 of 51.7 nM for human COX-2, exerts anti-inflammatory and analgesic effects in various rodent models by inhibiting NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, the phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS .
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