1 Result for "

CRBN ligand898

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CRBN ligand898" in MCE Product Catalog:

Cat. No.: HY-W947273
CAS No.: 2766178-72-5
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

CRBN ligand-898 is a CRBN ligand with a Kd of 216 nM. CRBN ligand-898 binds to CRBN, and when incorporated into proteolysis targeting chimeras (PROTACs), mediates degradation of intended target proteins. CRBN ligand-898 does not induce degradation of IMiD-associated neosubstrates Ikaros (IKZF1) and Aiolos (IKZF3). CRBN ligand-898 can be used to synthesize PROTACs .
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