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Caffeic acid (Standard)

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By Targets:	Apoptosis (1) Drug Intermediate (1) Endogenous Metabolite (2) Lipoxygenase (1) NF-κB (1) Reference Standards (5) TRP Channel (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (3) Neurological Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0172R

Caffeic acid (Standard)	Reference Standards TRP Channel Lipoxygenase Endogenous Metabolite	Inflammation/Immunology Cancer
Caffeic acid (Standard) is the analytical standard of Caffeic acid. This product is intended for research and analytical applications. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).

HY-N0274R

Caffeic acid phenethyl ester (Standard)	NF-κB Apoptosis Reference Standards	Inflammation/Immunology Cancer
Caffeic acid phenethyl ester (Standard) is the analytical standard of Caffeic acid phenethyl ester. This product is intended for research and analytical applications. Caffeic acid phenethyl ester is a NF-κB inhibitor.

HY-121231R

*trans-Caffeic* acid (Standard)**	Others Reference Standards	Others
trans-Caffeic acid (Standard) is the analytical standard of trans-Caffeic acid. This product is intended for research and analytical applications. trans-Caffeic acid is a growth stimulator that enhances the elongation growth of coleoptile sections .

HY-113357R

m-Coumaric acid (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease Inflammation/Immunology
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats .

HY-116284R

Methyl β-D-glucopyranoside (Standard) Methyl β-D-glucoside (Standard)	Reference Standards Drug Intermediate	Others
Methyl β-D-glucopyranoside (Methyl β-D-glucoside) (Standard) is the analytical standard of Methyl β-D-glucopyranoside. This product is intended for research and analytical applications. Methyl β-D-glucopyranoside is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside).

Caffeic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Plants Endogenous metabolite Source Classification	Reference Standards TRP Channel Lipoxygenase Endogenous Metabolite
Caffeic acid (Standard) is the analytical standard of Caffeic acid. This product is intended for research and analytical applications. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).

Caffeic acid phenethyl ester (Standard)	Structural Classification Animals Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Source Classification	NF-κB Apoptosis Reference Standards
Caffeic acid phenethyl ester (Standard) is the analytical standard of Caffeic acid phenethyl ester. This product is intended for research and analytical applications. Caffeic acid phenethyl ester is a NF-κB inhibitor.

*trans-Caffeic* acid (Standard)**	Structural Classification Ketones, Aldehydes, Acids Labiatae Phenols Polyphenols Centaurea benedicta (L.) L. Plants Source Classification	Others Reference Standards
trans-Caffeic acid (Standard) is the analytical standard of trans-Caffeic acid. This product is intended for research and analytical applications. trans-Caffeic acid is a growth stimulator that enhances the elongation growth of coleoptile sections .

m-Coumaric acid (Standard)	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Caffeic acid (Standard)

Inhibitors & Agonists

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Natural
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