588-30-7
Chemical Structure
m-Coumaric acid
- CAS No.: 588-30-7
- Formula:C9H8O3
- Molecular Weight:164.16
IUPAC Name: (E)-3-(3-hydroxyphenyl)acrylic acid
InChIKey: KKSDGJDHHZEWEP-SNAWJCMRSA-N
SMILES: O=C(O)/C=C/C1=CC=CC(O)=C1
Biological Activity: m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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m-Coumaric acid | 99.81% | m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats. | ||||||||||||||||||||
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m-Coumaric acid (Standard) | 99.91% | m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats. | ||||||||||||||||||||
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m-Coumaric acid-13C3 | m-Coumaric acid-13C3 is the 13C-labeled m-Coumaric acid. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. | |||||||||||||||||||||
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References
- [1]. Ito H, et al. Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells. Biosci Biotechnol Biochem. 2008 Mar;72(3):885-8. [Content Brief]
- [2]. Cabanes, J., et al., (1984). Kinetic study on the slow inhibition of epidermis tyrosinase by m-coumaric acid. Biochimica et biophysica acta, 790(2), 101–107. [Content Brief]
- [3]. Moselhy Said Salama, et al., m-Coumaric acid attenuates non-catalytic protein glycosylation in the retinas of diabetic rats. Journal of Pesticide Science. Online ISSN : 1349-0923. ISSN-L : 0385-1559.
