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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Carboxylesterase-IN-2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Carboxylesterase-IN-2" in MCE Product Catalog:
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Carboxylesterase-IN-2 (compound 4u) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-2 has the potential for the research of cancer disease .
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1 Cited Publications
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Cat. No.: HY-114118S
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Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family
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Cat. No.: HY-114118S1
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Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family
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Cat. No.: HY-N3474
CAS No.: 94805-83-1
Category:
Flavonols other families Flavonoids Other Diseases Phenols Polyphenols Plants Disease Research Fields
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Cat. No.: HY-P2424
CAS No.: 144396-38-3
Synonyms: CCK-J
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Cat. No.: HY-184061
CAS No.: 2590661-64-4
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Carboxylesterase 2-IN-1 is a potent carboxylesterase CES2 inhibitor with an IC50 of 0.13 μM. Carboxylesterase 2-IN-1 blocks the hydrolysis of fluorescein diacetate by CES2 via non-competitive inhibition. Carboxylesterase 2-IN-1 also effectively inhibits adipogenesis induced in mouse preadipocytes .
Cat. No.: HY-187682
CAS No.: 27783-53-5
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Deacetyl acebutolol is a disinfection by-product and in vivo deacetylated metabolite of Acebutolol (HY-17497). Deacetyl acebutolol is generated from Acebutolol via a series of reactions including chlorination, dealkylation, hydroxylation and oxidation. In vivo, Deacetyl acebutolol is produced by the carboxylesterase CES2-catalyzed hydrolysis of Acebutolol. Deacetyl acebutolol can be used in the research of arrhythmia [2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
