Carboxylesterase-IN-2
Based on 1 Customer Validation
Carboxylesterase-IN-2 (compound 4u) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-2 has the potential for the research of cancer disease.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 2764748-88-9
- Formula: C13H12N4OS
- Molecular Weight:272.33
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Metabolism/Protease Compound Library
HY-L012
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Stem Cell Signaling Compound Library
HY-L017
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Wnt/Hedgehog/Notch Compound Library
HY-L020
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Cytoskeleton Compound Library
HY-L060
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Neuroprotective Compound Library
HY-L070
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Anti-Breast Cancer Compound Library
HY-L074
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Protein-protein Interaction Inhibitor Library
HY-L109
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Extracellular Vesicles (EVs) Compound Library
HY-L168
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 2764748-88-9
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Appearance Solid
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Molecular Weight 272.33
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Formula C13H12N4OS
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Color Light yellow to yellow
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SMILES
O=C1NN=C2C=CC(SC3=CC=C(C)C(C)=C3)=NN21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (183.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.6720 mL | 18.3601 mL | 36.7202 mL | 91.8004 mL |
| 5 mM | 0.7344 mL | 3.6720 mL | 7.3440 mL | 18.3601 mL | |
| 10 mM | 0.3672 mL | 1.8360 mL | 3.6720 mL | 9.1800 mL | |
| 15 mM | 0.2448 mL | 1.2240 mL | 2.4480 mL | 6.1200 mL | |
| 20 mM | 0.1836 mL | 0.9180 mL | 1.8360 mL | 4.5900 mL | |
| 25 mM | 0.1469 mL | 0.7344 mL | 1.4688 mL | 3.6720 mL | |
| 30 mM | 0.1224 mL | 0.6120 mL | 1.2240 mL | 3.0600 mL | |
| 40 mM | 0.0918 mL | 0.4590 mL | 0.9180 mL | 2.2950 mL | |
| 50 mM | 0.0734 mL | 0.3672 mL | 0.7344 mL | 1.8360 mL | |
| 60 mM | 0.0612 mL | 0.3060 mL | 0.6120 mL | 1.5300 mL | |
| 80 mM | 0.0459 mL | 0.2295 mL | 0.4590 mL | 1.1475 mL | |
| 100 mM | 0.0367 mL | 0.1836 mL | 0.3672 mL | 0.9180 mL |
Carboxylesterase-IN-2 Related Classifications
HY-142688 Related Classifications
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