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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Cas9-IN-2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Cas9-IN-2" in MCE Product Catalog:
Cat. No.: HY-144119
CAS No.: 1030133-34-6
Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications .
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3 Cited Publications
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PolQi2 is a PolΘ inhibitor that targets and inhibits alt-EJ (alternative end-joining) repair by inhibiting the helicase domain at the N-terminus of PolΘ. PolQi2 enhances the precision and integration efficiency of gene editing at different loci and in various cell lines. Furthermore, the combined use of PolQi2 with DNA-PK inhibitors reduces the off-target effects of Cas9. PolQi2 can be used in gene editing research .
Cat. No.: HY-174793
The Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and a green fluorescent protein (GFP), which could be used in genome engineering experiments. The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.
Cat. No.: HY-188110
Cas9-T2A-GFP mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA. Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments.
Cat. No.: HY-188108
Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP). Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP) encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments. N1-Methylpseudo-UTP can reduce the immunogenicity of the generated mRNA.
Cat. No.: HY-188109
Target:
Research Areas:
Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP). Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP) encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments. N1-Methylpseudo-UTP can reduce the immunogenicity of the generated mRNA.
Cat. No.: HY-150279R
CAS No.: 2565638-16-4
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Research Areas:
PolQi2 (Standard) is the analytical standard of PolQi2 (HY-150279). This product is intended for research and analytical applications. PolQi2 is a PolΘ inhibitor that targets and inhibits alt-EJ (alternative end-joining) repair by inhibiting the helicase domain at the N-terminus of PolΘ. PolQi2 enhances the precision and integration efficiency of gene editing at different loci and in various cell lines. Furthermore, the combined use of PolQi2 with DNA-PK inhibitors reduces the off-target effects of Cas9. PolQi2 can be used in gene editing research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
