Cas9-IN-2
Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications.
For research use only. We do not sell to patients.
- CAS No.: 1030133-34-6
- Formula: C21H27N5O4S2
- Molecular Weight:477.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Cas9-IN-1 (compound 2) (200 and 500 μM; overnight) helps the E. coli selection strain to survive SpyCas9-induced killing[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1030133-34-6
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Molecular Weight 477.60
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Formula C21H27N5O4S2
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SMILES
O=S(NC1=NOC(C)=C1)(C2=C(C)N(C(C3=NC(C)=C(C(N4CCC(CC4)C)=O)S3)=C2)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)