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Isoforms Recommended:	Csk

Results for "

Csk

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AAK1 (1) Akt (2) Apoptosis (2) Aurora Kinase (1) Bcr-Abl (3) Biochemical Assay Reagents (1) c-Kit (1) CaMK (1) CDK (2) Cyclin G-associated Kinase (GAK) (1) Drug Derivative (1) EGFR (1) Ferroptosis (2) IKK (2) Interleukin Related (2) LIM Kinase (LIMK) (2) MAP4K (1) MAPKAPK2 (MK2) (1) NF-κB (2) NO Synthase (2) p38 MAPK (3) PKC (3) PROTAC Linkers (1) PROTACs (3) Pyk2 (1) Raf (1) Reference Standards (1) Salt-inducible Kinase (SIK) (2) Small Interfering RNA (siRNA) (3) Src (5) Tie (1) Toll-like Receptor (TLR) (11) ULK (2) VEGFR (1) Wee1 (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (2) Infection (7) Inflammation/Immunology (9) Metabolic Disease (1)
Click Chemistry:	PROTAC Synthesis (1) Alkynes (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1180A

Pam3CSK4 TFA 15+ Cited Publications Pam3Cys-Ser-(Lys)4 TFA	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC₅₀ of 0.47 ng/mL for human TLR1/2 .

HY-108471

CU-CPT22 10+ Cited Publications	Toll-like Receptor (TLR)	Cancer
CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam₃CSK₄) binding to TLR1/2 with a K_i of 0.41 µM. CU-CPT22 blocks Pam₃CSK₄-induced TLR1/2 activation with an IC₅₀ of 0.58 µM .

HY-112146

MMG-11 5 Publications Verification	Toll-like Receptor (TLR)	Inflammation/Immunology
MMG-11 is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC₅₀s of 1.7 µM for Pam₃CSK₄-induced hTLR2/1 and 5.7 µM for Pam₂CSK₄-induced hTLR2/6 responses .

HY-15196

TAK-285 3 Publications Verification	EGFR	Cancer
TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC₅₀ of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity . TAK-285 can cross the blood-brain barrier (BBB) .

HY-122113

PD173952 1 Publications Verification	Src Bcr-Abl Apoptosis Wee1	Cancer
PD173952 is a tyrosine kinases inhibitor with IC₅₀s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and *Csk, respectively. PD173952 is also a potent Myt1* kinase inhibitor with a K_i of 8.1 nM. PD173952 induces apoptosis .

HY-130254

CSK-IN-1 3 Publications Verification	Src	Inflammation/Immunology Cancer
CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) with IC₅₀ values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. CSK-IN-1 shows the ability to increase T cell proliferation induced by T cell receptor signaling .

HY-P1181A

Pam2CSK4 TFA 1 Publications Verification	Toll-like Receptor (TLR) NO Synthase IKK Akt PKC NF-κB p38 MAPK Interleukin Related	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pam2CSK4 TFA is a TLR2 agonist. Pam2CSK4 TFA induces the expression of iNOS and NO in macrophage cell lines via TBK1 and MyD88 molecules. Pam2CSK4 TFA activates the NF-κB and Bruton's tyrosine kinase signaling pathways in platelets, and promotes platelet-endothelial cell interactions. TLR2 activation triggered by Pam2CSK4 TFA expands myeloid-derived suppressor cells (MDSCs) and suppresses anti-tumor immune responses in the tumor microenvironment. Pam2CSK4 TFA acts as a Th2-polarizing adjuvant in mouse vaccine models against Leishmania major and Brugia malayi. Pam2CSK4 TFA can be used in the research of various diseases, including thromboinflammatory diseases, sepsis, atherosclerosis, heart failure, influenza, lymphoma, melanoma, cutaneous leishmaniasis and lymphatic filariasis .

HY-P1180

Pam3CSK4 Pam3Cys-Ser-(Lys)4	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC₅₀ of 0.47 ng/mL for human TLR1/2 .

HY-P1181

Pam2CSK4	Toll-like Receptor (TLR) NO Synthase IKK Akt PKC NF-κB p38 MAPK Interleukin Related	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pam2CSK4 is a TLR2 agonist. Pam2CSK4 induces the expression of iNOS and NO in macrophage cell lines via TBK1 and MyD88 molecules. Pam2CSK4 activates the NF-κB and Bruton's tyrosine kinase signaling pathways in platelets, and promotes platelet-endothelial cell interactions. TLR2 activation triggered by Pam2CSK4 expands myeloid-derived suppressor cells (MDSCs) and suppresses anti-tumor immune responses in the tumor microenvironment. Pam2CSK4 acts as a Th2-polarizing adjuvant in mouse vaccine models against Leishmania major and Brugia malayi. Pam2CSK4 can be used in the research of various diseases, including thromboinflammatory diseases, sepsis, atherosclerosis, heart failure, influenza, lymphoma, melanoma, cutaneous leishmaniasis and lymphatic filariasis .

HY-12291

HG6-64-1 HMSL 10017-101-1	Raf Apoptosis	Cancer
HG6-64-1 (HMSL 10017-101-1) is a B-raf kinase modulator.HG6-64-1 modulates B-raf kinase activity, including the V600E mutant form and the drug-resistant gatekeeper mutation T529I. HG6-64-1 is a germinal center kinase inhibitor. HG6-64-1 induces cell cycle arrest and apoptosis. HG6-64-1 can be used for the research of diffuse large B-cell lymphoma (DLBCL) .

HY-137345

DB-3-291	PROTACs Toll-like Receptor (TLR)	Cancer
DB-3-291 is potent and selective PROTAC *CSK* degrader, with a K_d of 1 nM (Pink: CSK ligand (HY-131669); Blue: E3 ligase ligand (HY-103597); Black: linker (HY-N2407)) .

HY-148061

DB1113	PROTACs Bcr-Abl CDK Salt-inducible Kinase (SIK) Cyclin G-associated Kinase (GAK) MAP4K MAPKAPK2 (MK2) Ferroptosis ULK LIM Kinase (LIMK)	Cancer
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-112146A

MMG-11 quarterhydrate 5 Publications Verification	Toll-like Receptor (TLR)	Inflammation/Immunology
MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC₅₀s of 1.7 μM for Pam₃CSK₄-induced hTLR2/1 and 5.7 μM for Pam₂CSK₄-induced hTLR2/6 responses .

HY-130504

Propargyl-PEG1-acid 1 Publications Verification	PROTAC Linkers	Cancer
Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib(HY-10997)-based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 μM . Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-148063

DB0614	PROTACs AAK1 Aurora Kinase CaMK CDK Ferroptosis Salt-inducible Kinase (SIK) LIM Kinase (LIMK) ULK	Metabolic Disease
DB0614 is a PROTAC based on Cereblon ligand, which is a selective and potent targeted protein degrader of NEK9 inhibitor. DB0614 can degrade ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2 and ULK1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity .(Blue: Thalidomide-4-OH (HY-103596), Black: linker, Pink: FLT3-IN-17 (HY-148070))

HY-P1405

Pam3CSK4-Biotin Pam3Cys-Ser-(Lys)4-Biotin	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4-Biotin is biotinylated Pam3CSK4. Pam3CSK4-Biotin is a Toll-like receptor 1/2 (TLR1/2) agonist .

HY-P1180B

Pam3CSK4 trihydrochloride Pam3Cys-Ser-(Lys)4 trihydrochloride	Biochemical Assay Reagents	Others
Pam3Cys-Ser-(Lys)4 trihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P1405A

Pam3CSK4-Biotin TFA Pam3Cys-Ser-(Lys)4-Biotin TFA	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4-Biotin (Pam3Cys-Ser-(Lys)4-Biotin) TFA is biotinylated Pam3CSK4. Pam3CSK4-Biotin TFA is a Toll-like receptor 1/2 (TLR1/2) agonist .

HY-118105

RK-20448	Src VEGFR Tie	Infection Cancer
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R and Tie-2 with IC₅₀ values of 0.24, 1.19, 10.74 and 5.85 µM, respectively. RK-20448 also inhibits BLK, *Csk, Fyn* and Lyn with IC₅₀ values of 0.37, 4.27, 2.03 and 0.43 µM, respectively. RK-20448 is the cis isomer of A-419259 (HY-15764) .

HY-P10527

CSK substrate	Src	Others
CSK substrate is a specific substrate for C-terminal Src kinase (CSK), which binds CSK and downregulates the Src family members. CSK substrate preferentially phosphorylates certain amino acid residues that are distinct from the conserved Src C-terminal sequence .

HY-RS03238

CSK Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CSK Human Pre-designed siRNA Set A contains three designed siRNAs for CSK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CSK Human Pre-designed siRNA Set A CSK Human Pre-designed siRNA Set A

HY-W114420

3-Methyl-L-tyrosine	PKC Drug Derivative	Cancer
3-Methyl-L-tyrosine is a derivative of L-Tyrosine (HY-N0473). Structurally, 3-Methyl-L-tyrosine features a methyl modification at the third position of the aromatic ring of L-Tyrosine. As a substrate for the protein tyrosine kinase *Csk, 3-Methyl-L-tyrosine's relative catalytic efficiency (kcat/Km) is 38% of L-Tyrosine, indicating that the methyl modification impacts the processing efficiency of Gsk* significantly. 3-Methyl-L-tyrosine helps to deepen the understanding of Gsk's molecular recognition mechanisms of its substrates, which is crucial for developing specific inhibitors targeting Gsk .

HY-RS16760

Csk Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Csk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Csk Mouse Pre-designed siRNA Set A Csk Mouse Pre-designed siRNA Set A

HY-RS23199

Csk Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Csk Rat Pre-designed siRNA Set A contains three designed siRNAs for Csk gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Csk Rat Pre-designed siRNA Set A Csk Rat Pre-designed siRNA Set A

HY-18909

Multi-kinase-IN-11	Src Bcr-Abl Pyk2 p38 MAPK c-Kit	Others
Multi-kinase-IN-11 (Compound 1a) is a DFG-out conformation-targeted multi-kinase inhibitor, including SRC, LCK, ABL, PYK2, CSK, HCK, P38 and C-KIT. Multi-kinase-IN-11 serves as a scaffold for the preparation of fluorescently labeled binding probes and affinity matrices .

HY-108471R

CU-CPT22 (Standard)	Reference Standards Toll-like Receptor (TLR)	Cancer
CU-CPT22 (Standard) is the analytical standard of CU-CPT22 (HY-108471). This product is intended for research and analytical applications. CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 with a K_i of 0.41 µM. CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation with an IC₅₀ of 0.58 µM .

Pam3CSK4 trihydrochloride Pam3Cys-Ser-(Lys)4 trihydrochloride	Biochemical Assay Reagents
Pam3Cys-Ser-(Lys)4 trihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P1180A

Pam3CSK4 TFA 15+ Cited Publications Pam3Cys-Ser-(Lys)4 TFA	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC₅₀ of 0.47 ng/mL for human TLR1/2 .

HY-P1181A

Pam2CSK4 TFA 1 Publications Verification	Toll-like Receptor (TLR) NO Synthase IKK Akt PKC NF-κB p38 MAPK Interleukin Related	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pam2CSK4 TFA is a TLR2 agonist. Pam2CSK4 TFA induces the expression of iNOS and NO in macrophage cell lines via TBK1 and MyD88 molecules. Pam2CSK4 TFA activates the NF-κB and Bruton's tyrosine kinase signaling pathways in platelets, and promotes platelet-endothelial cell interactions. TLR2 activation triggered by Pam2CSK4 TFA expands myeloid-derived suppressor cells (MDSCs) and suppresses anti-tumor immune responses in the tumor microenvironment. Pam2CSK4 TFA acts as a Th2-polarizing adjuvant in mouse vaccine models against Leishmania major and Brugia malayi. Pam2CSK4 TFA can be used in the research of various diseases, including thromboinflammatory diseases, sepsis, atherosclerosis, heart failure, influenza, lymphoma, melanoma, cutaneous leishmaniasis and lymphatic filariasis .

HY-P1180

Pam3CSK4 Pam3Cys-Ser-(Lys)4	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC₅₀ of 0.47 ng/mL for human TLR1/2 .

HY-P1181

Pam2CSK4	Toll-like Receptor (TLR) NO Synthase IKK Akt PKC NF-κB p38 MAPK Interleukin Related	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pam2CSK4 is a TLR2 agonist. Pam2CSK4 induces the expression of iNOS and NO in macrophage cell lines via TBK1 and MyD88 molecules. Pam2CSK4 activates the NF-κB and Bruton's tyrosine kinase signaling pathways in platelets, and promotes platelet-endothelial cell interactions. TLR2 activation triggered by Pam2CSK4 expands myeloid-derived suppressor cells (MDSCs) and suppresses anti-tumor immune responses in the tumor microenvironment. Pam2CSK4 acts as a Th2-polarizing adjuvant in mouse vaccine models against Leishmania major and Brugia malayi. Pam2CSK4 can be used in the research of various diseases, including thromboinflammatory diseases, sepsis, atherosclerosis, heart failure, influenza, lymphoma, melanoma, cutaneous leishmaniasis and lymphatic filariasis .

HY-P1405

Pam3CSK4-Biotin Pam3Cys-Ser-(Lys)4-Biotin	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4-Biotin is biotinylated Pam3CSK4. Pam3CSK4-Biotin is a Toll-like receptor 1/2 (TLR1/2) agonist .

HY-P1180B

Pam3CSK4 trihydrochloride Pam3Cys-Ser-(Lys)4 trihydrochloride	Biochemical Assay Reagents	Others
Pam3Cys-Ser-(Lys)4 trihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P11423

CSK peptide	Peptides	Others
CSK peptide is a peptide that improves transport of macromolecules across the intestinal mucosal barrier targeting goblet cells. CSK peptide can be used for oral delivery system research .

HY-P1405A

Pam3CSK4-Biotin TFA Pam3Cys-Ser-(Lys)4-Biotin TFA	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Pam3CSK4-Biotin (Pam3Cys-Ser-(Lys)4-Biotin) TFA is biotinylated Pam3CSK4. Pam3CSK4-Biotin TFA is a Toll-like receptor 1/2 (TLR1/2) agonist .

HY-P10527

CSK substrate	Src	Others
CSK substrate is a specific substrate for C-terminal Src kinase (CSK), which binds CSK and downregulates the Src family members. CSK substrate preferentially phosphorylates certain amino acid residues that are distinct from the conserved Src C-terminal sequence .

HY-P5527F

FAM-CSKtide	Peptides	Others
FAM-CSKtide is a biological active peptide. (This is a FAM labeled peptide substrate (Abs/Em = 494/521 nm) for C-terminal Src kinase (Csk) and many other kinases such as Axl, cKit, ERBB4, Fes, Flt3, IGF-1 R, MET, MUSK, PYK2, Ret, TIE2, TrkA, VEGF-R1 and VEGF-R2.)

Recombinant Proteins Recommended:

Species:	Human (1) Mouse (2)
Tag:	His (1) Tag Free (1) GST (2)
Source:	Sf9 insect cells (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P75322

	CSK Protein, Mouse (sf9) Tyrosine-protein kinase Csk; C-Src kinase; Csk	Mouse	Sf9 insect cells
	CSK protein is a non-receptor tyrosine protein kinase that regulates cell growth, differentiation, migration and immune responses by phosphorylating Src family kinases (SFK) (such as LCK, SRC, HCK, FYN, LYN, CSK or YES1) . This phosphorylation induces SFK to form an inactive conformation, thereby inhibiting signaling by receptors such as T cell receptor (TCR) and B cell receptor (BCR). CSK Protein, Mouse (sf9) is the recombinant mouse-derived CSK protein, expressed by Sf9 insect cells , with tag free.

HY-P72957

	CSK Protein, Mouse (Active, sf9, His-GST) Tyrosine-protein kinase Csk; C-Src kinase; Csk	Mouse	Sf9 insect cells
	CSK protein is a non-receptor tyrosine protein kinase that regulates cell growth, differentiation, migration and immune responses by phosphorylating Src family kinases (SFK) (such as LCK, SRC, HCK, FYN, LYN, CSK or YES1) . This phosphorylation induces SFK to form an inactive conformation, thereby inhibiting signaling by receptors such as T cell receptor (TCR) and B cell receptor (BCR). CSK Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived CSK protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P72956

	CSK Protein, Human (Active, sf9, GST) Tyrosine-protein kinase Csk; C-Src kinase; Csk	Human	Sf9 insect cells
	CSK is a non-receptor tyrosine protein kinase that critically regulates cell growth, differentiation, migration and immune responses by phosphorylating tyrosine residues in the C-terminal tail of Src family kinases (SFK). This induces an inactive conformation through intramolecular interactions with the SH2 domain of SFK. CSK Protein, Human (Active, sf9, GST) is the recombinant human-derived CSK protein, expressed by Sf9 insect cells , with N-GST labeled tag.

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Host:	Mouse (5) Rabbit (2)
Reactivity:	Human (7) Rat (6) Mouse (5) Monkey (3)
Application:	IHC-P (2) ICC/IF (4) IP (1) WB (7) FC (5) ELISA (4)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (7)
Clonality:	Monoclonal (5) Monoclonal Antibody (1) Recombinant (2)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84308

	CSK Antibody (YA4005) MGC117393; Csk	WB, ICC/IF, FC, ELISA	Human, Mouse, Monkey, Rat
	CSK Antibody (YA4005) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CSK.

HY-P84308A

	CSK Antibody (YA4005)(PBS only) MGC117393; Csk	WB, ICC/IF, FC, ELISA	Human, Mouse, Monkey, Rat
	CSK Antibody (YA4005) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CSK.

HY-P85111

	CSK Antibody (YA4803) Csk; Tyrosine-protein kinase Csk; C-Src kinase; Protein-tyrosine kinase CYL	WB, ICC/IF, FC, ELISA	Human, Mouse, Rat, Monkey
	CSK Antibody (YA4803) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CSK.

HY-P85546

	CSK Antibody (YA5238) C SRC; C SRC kinase; C src Tyrosine Kinase; C-SRC kinase; c-src tyrosine kinase; Csk A; Csk; Csk_HUMAN; CYTOPLASMIC TYROSINE KINASE; MGC112926; MGC117393; MGC154049; P60 Src; Protein tyrosine kinase CYL; Protein-tyrosine kinase CYL; Proto oncogene tyrosine protein kinase; Tyrosine protein kinase Csk; Tyrosine protein kinase Csk; Tyrosine-protein kinase Csk; zgc:154049.	WB, ICC/IF	Human, Rat
	CSK Antibody (YA5238) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CSK.

HY-P82997

	CSK Antibody (YA2742) Csk; Tyrosine-protein kinase Csk; C-Src kinase; Protein-tyrosine kinase CYL	WB, IHC-P	Human, Mouse, Rat
	CSK Antibody (YA2742) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CSK.

HY-P82223

	PAG1 Antibody (YA1968) CBP; Csk binding protein; PAG; PAG1	WB, IHC-P, IP, FC	Human, Mouse, Rat
	PAG1 Antibody (YA1968) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAG1.

HY-P85264

	MATK Antibody (YA4956) MATK; CTK; HYL; Megakaryocyte-associated tyrosine-protein kinase; Csk homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTK	WB, FC, ELISA	Human
	MATK Antibody (YA4956) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MATK.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-130504

Propargyl-PEG1-acid 1 Publications Verification		Alkynes PROTAC Synthesis
Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib(HY-10997)-based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 μM . Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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