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Pam3CSK4 trihydrochloride

(Synonyms: Pam3Cys-Ser-(Lys)4 trihydrochloride)
19 Cited Publications
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Based on 19 publication(s) in Google Scholar

Pam3Cys-Ser-(Lys)4 trihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

  • CAS No.: 112208-04-5
  • Formula: C81H159Cl3N10O13S
  • Molecular Weight:1619.61
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Pam3CSK4 trihydrochloride Chemical Structure
    Pam3CSK4 trihydrochloride Chemical Structure
  • Experimental Validation Results for Pam3CSK4 trihydrochloride
  • Experimental Validation Results for Pam3CSK4 trihydrochloride
  • Experimental Validation Results for Pam3CSK4 trihydrochloride
  • Experimental Validation Results for Pam3CSK4 trihydrochloride
  • Experimental Validation Results for Pam3CSK4 trihydrochloride
CAS No.: 112208-04-5
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  • Pam3CSK4 trihydrochloride Chemical Structure
    Pam3CSK4 trihydrochloride Chemical Structure
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    Pam3CSK4 trihydrochloride purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2025 Oct;26(10):1660-1672. [Abstract]

    Customer Validation
     Pam3CSK4 (Pam3; 1 µg/mL; 12 h). ELISA of secreted from wild-type BMDCs treated with PBS, BFP, GSDMD-NT, SK56, SK56 + GSDMD-NT, oxPAPC, SK56 + oxPAPC or pyroptotic cytomembrane fragments from mouse wild-type or Gsdmd−/− BMDMs as in c (NCF, PCF, PCF + SK56, PCFGsdmd−/−, PCFGsdmd−/− + SK56), treated or not treated with Pam3 for 12 h.

  • 1/16

    Pam3CSK4 trihydrochloride purchased from MedChemExpress. Usage Cited in: PLoS Pathog. 2024 Nov 5;20(11):e1012614. [Abstract]

    Customer Validation
     Pam3CSK4 (1 µg/mL; 12 h). Irg1 mRNA expression in neutrophils, pooled from three independent experiments.

  • 1/16

    Pam3CSK4 trihydrochloride purchased from MedChemExpress. Usage Cited in: J Pharm Anal. 2025 Jan;15(1):101054. [Abstract]

    Customer Validation
     Representative immunoblot images after the treatment of Oxymatrine (40 μM), Pam3CSK4 (3 μM), for five days.

  • 1/16

    Pam3CSK4 trihydrochloride purchased from MedChemExpress. Usage Cited in: Chin Herb Med. 2024 Apr 30;16(3):422-434. [Abstract]

    Customer Validation
     Pam3CSK4 (400 ng/mL; 4 h). Relative protein expression levels of Casp-1 p20 in BMDMs.

  • 1/16

    Pam3CSK4 trihydrochloride purchased from MedChemExpress. Usage Cited in: Chin Herb Med. 2024 Apr 30;16(3):422-434. [Abstract]

    Customer Validation
     Pam3CSK4 (400 ng/mL; 4 h). LPS-primed BMDMs with LJF, FF, or vehicle for 1 h and then stimulated with Pam3CSK4-primed BMDMs were pretreated with LJF, FF, or vehicle and then stimulated with transfected LPS. Activated caspase-1 (P20) and cleaved IL-1β (P17) in culture supernatants (SN) of BMDMs and NLRP3, ASC, pro-caspase-1(p45), pro-IL-1β in whole-cell lysates (WCL) by western blot analyses.

  • Pam3CSK4 trihydrochloride