2380027-49-4
Chemical Structure
CSK-IN-1
- CAS No.: 2380027-49-4
- Formula:C34H32ClFN8O4
- Molecular Weight:671.12
IUPAC Name: N-(3-chloro-4-(6-methoxypyrazolo[1,5-a]pyridine-3-carboxamido)phenyl)-1-(1-(3-cyano-3-methylbutanoyl)piperidin-4-yl)-5-fluoro-1H-indazole-3-carboxamide
InChIKey: LQQYARMJQBHKQQ-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2CCN(C(CC(C)(C#N)C)=O)CC2)C3=C1C=C(F)C=C3)NC4=CC=C(NC(C5=C6C=CC(OC)=CN6N=C5)=O)C(Cl)=C4
Biological Activity: CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. CSK-IN-1 shows the ability to increase T cell proliferation induced by T cell receptor signaling[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CSK-IN-1 | 98.04% | CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. CSK-IN-1 shows the ability to increase T cell proliferation induced by T cell receptor signaling. | ||||||||||||||||||||
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Keywords
