1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. MMG-11

MMG-11 

Cat. No.: HY-112146
Handling Instructions

MMG-11 is a potent and selective human TLR2 antagonist. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with an IC50 of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses.

For research use only. We do not sell to patients.

MMG-11 Chemical Structure

MMG-11 Chemical Structure

CAS No. : 313254-94-3

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Description

MMG-11 is a potent and selective human TLR2 antagonist. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with an IC50 of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].

IC50 & Target[1]

TLR2

 

References
Molecular Weight

306.27

Formula

C₁₅H₁₄O₇

CAS No.

313254-94-3

SMILES

OC1=C(O)C(O)=C(C(CC2=CC=C(C(OCC)=O)O2)=O)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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MMG-11
Cat. No.:
HY-112146
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MMG-11

Cat. No.: HY-112146