2769753-64-0

DB-3-291 Chemical Structure
2769753-64-0

Chemical Structure

DB-3-291

  • CAS No.: 2769753-64-0
  • Formula:C41H44ClN11O8S
  • Molecular Weight:886.37

IUPAC Name: N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-((4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-2-oxoethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide

InChIKey: NYBFKYHLTFWMOL-UHFFFAOYSA-N

SMILES: O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=CC=C3OCC(NCCCCNC(CN4CCN(C5=CC(NC6=NC=C(C(NC7=C(Cl)C=CC=C7C)=O)S6)=NC(C)=N5)CC4)=O)=O)=O

Biological Activity: DB-3-291 is potent and selective CSK PROTAC degrader, with a Kd of 1 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-137345
DB-3-291 99.08% DB-3-291 is potent and selective CSK PROTAC degrader, with a Kd of 1 nM.
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