1 Result for "

Cyclin A/B RxL-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cyclin A/B RxL-IN-1" in MCE Product Catalog:

Cat. No.: HY-175729
CAS No.: 3036231-62-3
Target:  

CDK

Research Areas:  

Cancer

Cyclin A/B RxL-IN-1 is a inhibitor targeting the Cyclin A/B RxL interaction at the hydrophobic patch (HP). Cyclin A/B RxL-IN-1 inhibits Cyclin A with an IC50 of 0.12 μM. Cyclin A/B RxL-IN-1 demonstrates antitumor efficacy in mouse cell line-derived xenograft (CDX) models. CDK-IN-19 can be used for the study of E2F-driven cancers such as small-cell lung cancer (SCLC) .
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