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2 Results for "
DFMO hydrochloride hydrate (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "DFMO hydrochloride hydrate (Standard)" in MCE Product Catalog:
Cat. No.: HY-B0744BR
CAS No.: 96020-91-6
Synonyms: DFMO hydrochloride hydrate (Standard); MDL-71782 hydrochloride hydrate (Standard); RMI-71782 hydrochloride hydrate (Standard); α-difluoromethylornithine hydrochloride hydrate (Standard)
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Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
Cat. No.: HY-187603
CAS No.: 211816-91-0
CGP 40215 is an S-adenosylmethionine decarboxylase inhibitor with an IC50 of 20.3 μM against Trypanosoma brucei brucei AdoMet decarboxylase. CGP 40215 blocks spermidine production and leads to putrescine accumulation. CGP 40215 inhibits polyamine biosynthesis in intact trypanosomes, acts synergistically with the ornithine decarboxylase inhibitor DFMO (HY-B0744) against CNS model infections, and ameliorates laboratory infections caused by multiple Trypanosoma brucei subspecies and Trypanosoma congolense isolates, including strains tolerant to standard trypanocides. CGP 40215 can be used for research on African trypanosomiasis and Chagas disease .
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