2 Results for "

Dexamethasone sodium phosphate solution

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Dexamethasone sodium phosphate solution" in MCE Product Catalog:

Cat. No.: HY-FLB1829A
CAS No.: 2392-39-4
Synonyms: Dexamethasone 21-phosphate disodium solution
Dexamethasone sodium phosphate solution is mainly composed of Dexamethasone phosphate disodium (HY-B1829A). Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate disodium is produced by introducing a phosphate ester group at the 21-position of the Dexamethasone molecule, forming a salt with sodium ions, thereby significantly improving water solubility. Dexamethasone phosphate disodium inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate disodium inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate disodium is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate disodium can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease) .
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Cat. No.: HY-FL128922
CAS No.: 14899-36-6
Synonyms: DXP solution
Target:  

Drug Intermediate

Research Areas:  

Others

Dexamethasone palmitate solution is mainly composed of Dexamethasone palmitate (HY-128922). Dexamethasone palmitate (DXP) is a proagent of Dexamethasone (HY-14648). Dexamethasone palmitate can be used for the research of inflammation .
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