1 Result for "

EGFR/CDK2-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EGFR/CDK2-IN-5" in MCE Product Catalog:

Cat. No.: HY-180242
Research Areas:  

Cancer

EGFR/CDK2-IN-5 is a potent dual EGFR and CDK2 inhibitor with IC50s of 17.30 and 212.10 nM, respectively. EGFR/CDK2-IN-5 also inhibits EGFR T790M with an IC50 of 123.8 nM. EGFR/CDK2-IN-5 exhibits potent anticancer activity. EGFR/CDK2-IN-5 induces G1 and S cell cycle arrest and apoptosis, accompanied by increased levels of caspase-3/9 and Bax, as well as decreased Bcl-2 levels. EGFR/CDK2-IN-5 can be used for the research of cancers, such as lung cancer, breast cancer, and leukemia .
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