1 Result for "

EGFR d747-752/P753S Recombinant Human Active Protein Kinase

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EGFR d747-752/P753S Recombinant Human Active Protein Kinase" in MCE Product Catalog:

Cat. No.: HY-E70702
Target:  

EGFR

Research Areas:  

Cancer

EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d747-752/P753S Recombinant Human Active Protein Kinase is a recombinant EGFR d747-752/P753S protein that can be used to study EGFR d747-752/P753S-related functions .
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