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Folic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (6) Androgen Receptor (2) Antibiotic (14) Antifolate (28) Apoptosis (6) Bacterial (27) Biochemical Assay Reagents (68) Carboxypeptidase (1) Dihydrofolate reductase (DHFR) (4) DNA/RNA Synthesis (22) Drug Derivative (5) Drug Intermediate (3) Drug Metabolite (13) Endogenous Metabolite (33) Environmental Pollutants (4) Ferroptosis (1) Fluorescent Dye (23) Folate Receptor (FR) (7) Fungal (2) Isotope-Labeled Compounds (28) Liposome (3) Parasite (11) PROTAC Linkers (1) Radionuclide-Drug Conjugates (RDCs) (2) Reactive Oxygen Species (ROS) (6) Reference Standards (20) VDAC (1)
By Research Areas:	Cancer (57) Cardiovascular Disease (7) Endocrinology (1) Infection (35) Inflammation/Immunology (22) Metabolic Disease (16) Neurological Disease (12)
Click Chemistry:	DBCO (5)
Oligonucleotides:	Pegylated Lipids (4) Polymers (2)

199

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Antibodies

Click Chemistry

Oligonucleotides

Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-16637

Folic acid Maximum Cited Publications 25 Publications Verification Vitamin B9; Vitamin M	Environmental Pollutants Endogenous Metabolite DNA/RNA Synthesis	Cardiovascular Disease Infection Neurological Disease Cancer
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-17556

Folinic acid 15+ Cited Publications leucovorin	Antifolate Endogenous Metabolite	Cancer
Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity .

HY-13664

Folinic acid calcium 15+ Cited Publications Leucovorin calcium; Calcium folinate	Antifolate Endogenous Metabolite	Cancer
Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .

HY-113046

5-Methyltetrahydrofolic acid 5+ Cited Publications 5-Methyl THF; 5-MTHF	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases .

HY-14781

Levomefolic acid 3 Publications Verification L-5-MTHF	Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis	Infection Cancer
Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-14518

Aminopterin 4-AminoFolic acid; APGA	Antifolate	Inflammation/Immunology Cancer
Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a K_i of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .

HY-W440888

DSPE-PEG2000-Folate DSPE-PEG2000(2000) Folate	Liposome Folate Receptor (FR)	Cancer
DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems [2].

HY-13615

Folate-FITC EC-17	Fluorescent Dye Folate Receptor (FR)	Cancer
Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .

HY-16637R

Folic acid (Standard) 1 Publications Verification Vitamin B9 (Standard); Vitamin M (Standard)	Reference Standards DNA/RNA Synthesis Endogenous Metabolite	Neurological Disease Cancer
Folic acid (Standard) is the analytical standard of Folic acid. This product is intended for research and analytical applications. Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-108251

Methotrexate metabolite 1 Publications Verification DAMPA	Antifolate Drug Metabolite Dihydrofolate reductase (DHFR) Parasite	Infection Inflammation/Immunology
Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC₅₀ values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation .

HY-B0946

Sulfamonomethoxine 1 Publications Verification	Antibiotic Bacterial	Infection
Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-A0130

Sulfalene Sulfametopyrazine; AS-18908	Parasite Bacterial	Infection Inflammation/Immunology
Sulfalene (Sulfametopyrazine) is an orally active antimalarial agent. Sulfalene competes with para-aminobenzoic acid in plasmodial and bacterial folic acid synthesis pathways. Sulfalene reduces trachoma-associated pathological changes. Sulfalene can be used for the research of acute falciparum malaria, Schistosoma mansoni infection, trachoma, chronic bronchitis, and bacteriuria in pregnancy .

HY-B0333

Sulfamethizole 2 Publications Verification	Antibiotic Bacterial	Infection
Sulfamethizole is a sulfathiazole antibiotic. Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli-mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli. Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms .

HY-16637D

Folic acid disodium Maximum Cited Publications 25 Publications Verification Vitamin B9 disodium; Vitamin M disodium	Endogenous Metabolite DNA/RNA Synthesis	Others Neurological Disease Cancer
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-16637S1

Folic acid-d4 Vitamin B9-d₄; Vitamin M-d₄	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid-d₄ is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-W1123936B

DBCO-PEG1000-FA DBCO-PEG1000-Folate	Folate Receptor (FR)	Cancer
DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-129398

Formiminoglutamic acid	Endogenous Metabolite	Metabolic Disease
Formiminoglutamic acid, an endogenous metabolite, could be an index of folic-acid deficiency .

HY-14781S1

Levomefolic acid-13C,d3 L-5-MTHF-¹³C,d₃	Isotope-Labeled Compounds DNA/RNA Synthesis Reactive Oxygen Species (ROS) Endogenous Metabolite	Others
Levomefolic acid- ¹³C,d₃ is the deuterium labeled Levomefolic acid (HY-14781) . Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-16637A

Folic acid sodium Vitamin B9 sodium; Vitamin M sodium	DNA/RNA Synthesis Endogenous Metabolite	Neurological Disease
Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-113046R

5-Methyltetrahydrofolic acid (Standard) 1 Publications Verification 5-Methyl THF (Standard); 5-MTHF (Standard)	Reference Standards Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.

HY-121652

Mefox	Drug Metabolite	Others
Mefox is a degradation product of folic acid (HY-16637) .

HY-16637S

Folic acid-d2 Vitamin B9-d₂; Vitamin M-d₂	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16637S5

Folic acid-13C6 Vitamin B9-¹³C₆; Vitamin M-¹³C₆	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-16637S3

Folic acid-13C5 Vitamin B9-¹³C₅; Vitamin M-¹³C₅	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-103396

Trimetrexate glucuronate 2 Publications Verification CI-898 glucuronate	Antifolate Bacterial	Infection Cancer
Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .

HY-W037819

6-Methylpterin	Drug Derivative	Metabolic Disease
6-Methylpterin is a derivative of the essential B vitamin Folic acid (HY-16637). 6-Methylpterin generates singlet oxygen and hydrogen peroxide when exposed to Photoirradiation. 6-Methylpterin can be used for the detection of pterins in urine .

HY-16637S4

Folic acid-13C5,15N Vitamin B9-¹³C₅,¹⁵N; Vitamin M-¹³C₅,¹⁵N	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Others
Folic acid- ¹⁵N, ¹³C₅ is the ¹³C₅ and ¹⁵N labeled Folic acid (HY-16637) .

HY-B0946S

Sulfamonomethoxine-d4	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Sulfamonomethoxine-d₄ is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-W1123936C

DBCO-PEG2000-FA DBCO-PEG2000-Folate	Folate Receptor (FR)	Others
DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-14781S2

Levomefolic acid-13C5 L-5-MTHF-¹³C₅	DNA/RNA Synthesis Endogenous Metabolite Reactive Oxygen Species (ROS)	Cancer
Levomefolic acid- ¹³C₅ is the ¹³C labeled Levomefolic acid . Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-400648

Folic acid methyl ester	Drug Metabolite	Cancer
Folic acid methyl ester is a methyl ester metabolite of folic acid that can be used in the study of neuropsychiatric conditions, such as depression ^{[1] ^.}

HY-121151

(±)-Methotrexate (±)-Amethopterin; (±)-CL14377; (±)-WR19039	Antifolate	Others
(±)-Methotrexate ((±)-Amethopterin) is a racemate of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of Folic acid into Tetrahydrofolate, and inhibiting DNA synthesis .

HY-W1123936D

DBCO-PEG3400-FA DBCO-PEG3400-Folate	Folate Receptor (FR)	Others
DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123932A

mPEG2000-FA mPEG2000-Folate	Biochemical Assay Reagents	Others
mPEG2000-FA (mPEG2000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-14781S3

Levomefolic acid-d3 L-5-MTHF-d₃	Isotope-Labeled Compounds DNA/RNA Synthesis Reactive Oxygen Species (ROS) Endogenous Metabolite	Infection Cancer
Levomefolic acid-d₃ (L-5-MTHF-d₃) is deuterium labeled Levomefolic acid. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-NP182

Folic acid/OVA	Biochemical Assay Reagents	Inflammation/Immunology
Folic acid/OVA is a conjugate of Folic acid (HY-16637) and ovalbumin that improves the stability and solubility of folic acid .

HY-NP182A

Folic acid-BSA FA-BSA	Biochemical Assay Reagents	Inflammation/Immunology
Folic acid-BSA (FA-BSA) is a conjugate of Folic acid (HY-16637) and BSA that improves the stability and solubility of Folic acid .

HY-W740790

*N-Acetyl folic* acid-d4**	Isotope-Labeled Compounds	Others
N-Acetyl folic acid-d₄ is the deuterium labeled N-Acetyl folic acid.

HY-14781A

Levomefolic acid magnesium L-5-MTHF magnesium	Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis	Infection Cancer
Levomefolic acid magnesium is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-14518R

Aminopterin (Standard) 4-AminoFolic acid (Standard); APGA (Standard)	Reference Standards Antifolate	Inflammation/Immunology Cancer
Aminopterin (Standard) is the analytical standard of Aminopterin. This product is intended for research and analytical applications. Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .

HY-W751746

*Dehydro Folic* Acid 1,5-Dimethyl Ester-13C5**	Isotope-Labeled Compounds	Others
Dehydro Folic Acid 1,5-Dimethyl Ester- ¹³C₅ is the ¹³C-labeled Dehydro Folic Acid 1,5-Dimethyl Ester.

HY-W751764

*Dehydro Folic* Acid 1,5-Dimethyl Ester-13C5,15N**	Isotope-Labeled Compounds	Others
Dehydro Folic Acid 1,5-Dimethyl Ester- ¹³C₅, ¹⁵N is the ¹³C- and ¹⁵N-labeled Dehydro Folic Acid 1,5-Dimethyl Ester.

HY-B0946R

Sulfamonomethoxine (Standard)	Reference Standards Antibiotic Bacterial	Infection
Sulfamonomethoxine (Standard) is the analytical standard of Sulfamonomethoxine (HY-B0946). This product is intended for research and analytical applications. Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-14518A

Aminopterin sodium 4-AminoFolic acid sodium; APGA sodium	Antifolate	Cancer
Aminopterin sodium (4-Aminofolic acid sodium) is an anti-tumor drug with immunosuppressive activity. Aminopterin sodium blocks the metabolism of folic acid by inhibiting the activity of dihydrofolate reductase, thereby affecting nucleic acid synthesis. Aminopterin sodium is mainly used to inhibit acute lymphoblastic leukemia and certain other types of cancer. Aminopterin sodium is also used clinically as an immunosuppressant to suppress autoimmune diseases .

HY-103396R

Trimetrexate glucuronate (Standard) CI-898 glucuronate (Standard)	Reference Standards Antifolate Bacterial	Infection Cancer
Trimetrexate (glucuronate) (Standard) is the analytical standard of Trimetrexate (glucuronate). This product is intended for research and analytical applications. Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .

HY-16637S2

*(Rac)-Folic* acid-13C5,15N** (Rac)-Vitamin B9-¹³C₅,¹⁵N; (Rac)-Vitamin M-¹³C₅,¹⁵N	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-A0130R

Sulfalene (Standard) Sulfametopyrazine (Standard); AS-18908 (Standard)	Reference Standards Parasite	Infection
Sulfalene (Standard) is the analytical standard of Sulfalene. This product is intended for research and analytical applications. Sulfalene (Sulfametopyrazine; AS-18908) is an orally active antimalarial agent. Sulfalene competes for para-aminobenzoic acid binding in plasmodial folic acid synthesis. Sulfalene, combined with Trimethoprim (HY-B0510), clears parasites, resolves fever, and resists induced resistance against drug-sensitive and drug-resistant Plasmodium falciparum. Sulfalene can be used for the research of acute falciparum malaria and Schistosoma mansoni infection .

HY-123098

Tetrahydromethotrexate	Antifolate Bacterial DNA/RNA Synthesis	Cancer
Tetrahydromethotrexate is a more potent folate antagonist than Methotrexate (HY-14519) in studies against certain bacteria (Streptococcus faecalis, Pediococcus erevisiae) and in animal models. Tetrahydromethotrexate is used in the research of cancer and autoimmune diseases .

HY-W1123936H

DBCO-PEG10000-FA DBCO-PEG10000-Folate	Folate Receptor (FR)	Others
DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936E

DBCO-PEG5000-FA DBCO-PEG5000-Folate	Folate Receptor (FR)	Others
DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

Art. -Nr.	Produktname	Type

HY-D1716

S0456	Fluorescent Dyes
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .

HY-D2844

FITC-PEG400-FA	Fluorescent Dyes
FITC-PEG400-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG400-FA can be used for fluorescent labeling and imaging .

HY-D2844D

FITC-PEG5000-FA	Fluorescent Dyes
FITC-PEG5000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG5000-FA can be used for fluorescent labeling and imaging .

HY-D2844A

FITC-PEG1000-FA	Fluorescent Dyes
FITC-PEG1000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG1000-FA can be used for fluorescent labeling and imaging .

HY-D2619

ICG PEG5000 FA	Fluorescent Dyes
ICG PEG5000 FA is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG5000 FA is widely used in drug delivery and biomaterial labeling (Ex/Em=785/813 nm).

HY-D2618

ICG PEG2000 FA	Fluorescent Dyes
ICG PEG2000 FA is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG2000 FA is widely used in drug delivery and biomaterial labeling (Ex/Em=785/813 nm).

HY-D2550

Cy5-PEG2000-FA	Fluorescent Dyes
Cy5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.

HY-D2551

Cy5-PEG5000-FA	Fluorescent Dyes
Cy5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.

HY-D2888A

RB-PEG600-FA Rhodamine B-PEG600-FA	Fluorescent Dyes
RB-PEG600-FA (Rhodamine B-PEG600-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG600-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888

RB-PEG400-FA Rhodamine B-PEG400-FA	Fluorescent Dyes
RB-PEG400-FA (Rhodamine B-PEG400-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG400-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888D

RB-PEG3400-FA Rhodamine B-PEG3400-FA	Fluorescent Dyes
RB-PEG3400-FA (Rhodamine B-PEG3400-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG3400-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2573

Cy5.5-PEG2000-FA	Fluorescent Dyes
Cy5.5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.

HY-D2435

MTX-PEG-Cy3

Fluorescent Dyes

CDDP-PEG-Cy3 is a MTX-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Methotrexate (Amethopterin; MTX) (HY-14519), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

HY-D2844C

FITC-PEG3400-FA	Fluorescent Dyes
FITC-PEG3400-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG3400-FA can be used for fluorescent labeling and imaging .

HY-D2844E

FITC-PEG10000-FA	Fluorescent Dyes
FITC-PEG10000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG10000-FA can be used for fluorescent labeling and imaging .

HY-D2844B

FITC-PEG2000-FA	Fluorescent Dyes
FITC-PEG2000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG2000-FA can be used for fluorescent labeling and imaging .

HY-D2524

Cy3-PEG5000-FA	Fluorescent Dyes
Cy3-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy3 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy3 is approximately 562-570 nm.

HY-D2888C

RB-PEG2000-FA Rhodamine B-PEG2000-FA	Fluorescent Dyes
RB-PEG2000-FA (Rhodamine B-PEG2000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG2000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888H

RB-PEG10000-FA Rhodamine B-PEG10000-FA	Fluorescent Dyes
RB-PEG10000-FA (Rhodamine B-PEG10000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG10000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888E

RB-PEG5000-FA Rhodamine B-PEG5000-FA	Fluorescent Dyes
RB-PEG5000-FA (Rhodamine B-PEG5000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG5000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888B

RB-PEG1000-FA Rhodamine B-PEG1000-FA	Fluorescent Dyes
RB-PEG1000-FA (Rhodamine B-PEG1000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG1000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2574

Cy5.5-PEG5000-FA	Fluorescent Dyes
Cy5.5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.

Art. -Nr.	Produktname	Type

HY-144009

DSPE-PEG-Folate, MW 3350	Biochemical Assay Reagents
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W053583

Tetraxetan

1 Publications Verification

DOTA

Biochemical Assay Reagents

Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., ⁶⁸Ga, ¹¹¹In, ¹⁷⁷Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .

HY-W440888

DSPE-PEG2000-Folate

DSPE-PEG2000(2000) Folate

Biochemical Assay Reagents

DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems [2].

HY-W1123936B

DBCO-PEG1000-FA

DBCO-PEG1000-Folate

Biochemical Assay Reagents

DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W440890

DSPE-PEG-Folate, MW 5000	Biochemical Assay Reagents
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W094517

Sodium phosphate dibasic heptahydrate

Biochemical Assay Reagents

Sodium phosphate dibasic heptahydrate is an orally active and osmotic laxative, often used as a component of over-the-counter gastrointestinal lavage drugs. Sodium phosphate dibasic heptahydrate draws water into the intestinal lumen, maintains electrical neutrality by retaining cations in the intestinal lumen, and thereby alters fecal volume, consistency and phosphate levels. Sodium phosphate dibasic heptahydrate can be used to generate self-assembled calcium phosphate tubular scaffolds, which support the adhesion, survival and elongation of mesenchymal stem cells. Sodium phosphate dibasic heptahydrate can be applied to research on factitious disorders and related fields .

HY-W010169

Sodium 4-aminobenzoate 1 Publications Verification	Biochemical Assay Reagents
Sodium 4-aminobenzoate is an intermediate in the synthesis of folic acid by bacteria, plants and fungi. Sodium 4-aminobenzoate has antibacterial and plant growth regulating properties .

HY-W053583R

Tetraxetan (Standard)

DOTA (Standard)

Biochemical Assay Reagents

Tetraxetan (Standard) is the analytical standard of Tetraxetan (HY-W053583). This product is intended for research and analytical applications. Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., ⁶⁸Ga, ¹¹¹In, ¹⁷⁷Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .

HY-W1123936C

DBCO-PEG2000-FA

DBCO-PEG2000-Folate

Biochemical Assay Reagents

DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)	Biochemical Assay Reagents
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000	Biochemical Assay Reagents
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W1123936D

DBCO-PEG3400-FA

DBCO-PEG3400-Folate

Biochemical Assay Reagents

DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123932A

mPEG2000-FA mPEG2000-Folate	Biochemical Assay Reagents
mPEG2000-FA (mPEG2000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-168940E

NH2-PEG600-COOH	Biochemical Assay Reagents
NH2-PEG600-COOH consists of an NH2 group, PEG units and a carboxyl group (-COOH). NH2-PEG600-COOH helps improve the biocompatibility of the resulting nanocomplexes in cancer cells. NH2-PEG600-COOH can be used in cancer-related research .

HY-NP182

Folic acid/OVA	Biochemical Assay Reagents
Folic acid/OVA is a conjugate of Folic acid (HY-16637) and ovalbumin that improves the stability and solubility of folic acid .

HY-NP182A

Folic acid-BSA FA-BSA	Biochemical Assay Reagents
Folic acid-BSA (FA-BSA) is a conjugate of Folic acid (HY-16637) and BSA that improves the stability and solubility of Folic acid .

HY-W1123936H

DBCO-PEG10000-FA

DBCO-PEG10000-Folate

Biochemical Assay Reagents

DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936E

DBCO-PEG5000-FA

DBCO-PEG5000-Folate

Biochemical Assay Reagents

DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123932

mPEG1000-FA mPEG1000-Folate	Biochemical Assay Reagents
mPEG1000-FA (mPEG1000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966B

BOC-NH-PEG1000-FA BOC-NH-PEG1000-Folate	Biochemical Assay Reagents
BOC-NH-PEG1000-FA (BOC-NH-PEG1000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966

BOC-NH-PEG400-FA BOC-NH-PEG400-Folate	Biochemical Assay Reagents
BOC-NH-PEG400-FA (BOC-NH-PEG400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W1123945

8-Arm-PEG400-FA 8-Arm-PEG400-Folate	Biochemical Assay Reagents
8-Arm-PEG400-FA (8-Arm-PEG400-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W888710D

FA-PEG2000-COOH Folate-PEG2000-COOH	Biochemical Assay Reagents
FA-PEG2000-COOH (Folate-PEG2000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-W888710E

FA-PEG3400-COOH Folate-PEG3400-COOH	Biochemical Assay Reagents
FA-PEG3400-COOH (Folate-PEG3400-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-W440888B

DSPE-PEG3400-Folate	Biochemical Assay Reagents
DSPE-PEG3400-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888A

DSPE-PEG1000-Folate	Biochemical Assay Reagents
DSPE-PEG1000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888C

DSPE-PEG5000-Folate	Biochemical Assay Reagents
DSPE-PEG5000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-179189H

FA-PEG10000-ACA Folate-PEG10000-ACA	Biochemical Assay Reagents
FA-PEG10000-ACA (Folate-PEG10000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-179189B

FA-PEG1000-ACA Folate-PEG1000-ACA	Biochemical Assay Reagents
FA-PEG1000-ACA (Folate-PEG1000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-179189C

FA-PEG2000-ACA Folate-PEG2000-ACA	Biochemical Assay Reagents
FA-PEG2000-ACA (Folate-PEG2000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-179189D

FA-PEG3400-ACA Folate-PEG3400-ACA	Biochemical Assay Reagents
FA-PEG3400-ACA (Folate-PEG3400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-179189E

FA-PEG5000-ACA Folate-PEG5000-ACA	Biochemical Assay Reagents
FA-PEG5000-ACA (Folate-PEG5000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-179189

FA-PEG400-ACA Folate-PEG400-ACA	Biochemical Assay Reagents
FA-PEG400-ACA (Folate-PEG400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-179189A

FA-PEG600-ACA Folate-PEG600-ACA	Biochemical Assay Reagents
FA-PEG600-ACA (Folate-PEG600-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-W1052215

FA-PEG1000-NH2 Folate-PEG1000-NH2	Biochemical Assay Reagents
FA-PEG1000-NH2 (Folate-PEG1000-NH2) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and NH2. Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-W1052215A

FA-PEG2000-NH2 Folate-PEG2000-NH2	Biochemical Assay Reagents
FA-PEG2000-NH2 (Folate-PEG2000-NH2) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and NH2. Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-W1052215D

FA-PEG5000-NH2 Folate-PEG5000-NH2	Biochemical Assay Reagents
FA-PEG5000-NH2 (Folate-PEG5000-NH2) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and NH2. Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-W1052215B

FA-PEG3400-NH2 Folate-PEG3400-NH2	Biochemical Assay Reagents
FA-PEG3400-NH2 (Folate-PEG3400-NH2) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and NH2. Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.

HY-W1052178H

FA-PEG600-Cholesterol Folate-PEG600-Cholesterol	Biochemical Assay Reagents
FA-PEG600-Cholesterol (Folate-PEG600-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1052178E

FA-PEG400-Cholesterol Folate-PEG400-Cholesterol	Biochemical Assay Reagents
FA-PEG400-Cholesterol (Folate-PEG400-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1052178

FA-PEG2000-Cholesterol Folate-PEG2000-Cholesterol	Biochemical Assay Reagents
FA-PEG2000-Cholesterol (Folate-PEG2000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1052178C

FA-PEG10000-Cholesterol Folate-PEG10000-Cholesterol	Biochemical Assay Reagents
FA-PEG10000-Cholesterol (Folate-PEG10000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1052178B

FA-PEG5000-Cholesterol Folate-PEG5000-Cholesterol	Biochemical Assay Reagents
FA-PEG5000-Cholesterol (Folate-PEG5000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1052178A

FA-PEG3400-Cholesterol Folate-PEG3400-Cholesterol	Biochemical Assay Reagents
FA-PEG3400-Cholesterol (Folate-PEG3400-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1052178D

FA-PEG1000-Cholesterol Folate-PEG1000-Cholesterol	Biochemical Assay Reagents
FA-PEG1000-Cholesterol (Folate-PEG1000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .

HY-W1123932B

mPEG5000-FA mPEG5000-Folate	Biochemical Assay Reagents
mPEG5000-FA (mPEG5000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966D

BOC-NH-PEG3400-FA BOC-NH-PEG3400-Folate	Biochemical Assay Reagents
BOC-NH-PEG3400-FA (BOC-NH-PEG3400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966E

BOC-NH-PEG5000-FA BOC-NH-PEG5000-Folate	Biochemical Assay Reagents
BOC-NH-PEG5000-FA (BOC-NH-PEG5000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966C

BOC-NH-PEG2000-FA BOC-NH-PEG2000-Folate	Biochemical Assay Reagents
BOC-NH-PEG2000-FA (BOC-NH-PEG2000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966H

BOC-NH-PEG10000-FA BOC-NH-PEG10000-Folate	Biochemical Assay Reagents
BOC-NH-PEG10000-FA (BOC-NH-PEG10000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

Art. -Nr.	Produktname	Category	Target	Chemical Structure

HY-16637

Folic acid Maximum Cited Publications 25 Publications Verification Vitamin B9; Vitamin M	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Endocrine diseases Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms other families Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Source Classification Cancer	Environmental Pollutants Endogenous Metabolite DNA/RNA Synthesis
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-17556

Folinic acid 15+ Cited Publications leucovorin	Natürliche Produkte Human Gut Microbiota Metabolites Classification of Application Fields Plants Moraceae Endogenous metabolite Disease Research Fields Morus alba Linn. Source Classification Cancer	Antifolate Endogenous Metabolite
Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity .

HY-13664

Folinic acid calcium 15+ Cited Publications Leucovorin calcium; Calcium folinate	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Antifolate Endogenous Metabolite
Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .

HY-113046

5-Methyltetrahydrofolic acid 5+ Cited Publications 5-Methyl THF; 5-MTHF	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases .

HY-14781

Levomefolic acid 3 Publications Verification L-5-MTHF	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis
Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-B1008

4-Aminobenzoic acid 1 Publications Verification PABA; p-Aminobenzoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Bacterial
4-Aminobenzoic acid is an intermediate in the synthesis of folic acid by bacteria, plants and fungi. 4-Aminobenzoic acid has antibacterial and plant growth regulating properties .

HY-B0080

Folinic acid calcium salt pentahydrate 15+ Cited Publications Leucovorin calcium salt pentahydrate	Natürliche Produkte Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Antifolate Endogenous Metabolite
Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .

HY-16637R

Folic acid (Standard) 1 Publications Verification Vitamin B9 (Standard); Vitamin M (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Plants Endogenous metabolite Source Classification	Reference Standards DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Standard) is the analytical standard of Folic acid. This product is intended for research and analytical applications. Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-N7123

Sulfacetamide 3 Publications Verification Sulphacetamide	Infection Classification of Application Fields Disease Research Fields	Environmental Pollutants Antibiotic Bacterial Fungal
Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .

HY-17556R

Folinic acid (Standard) leucovorin (Standard)	Natürliche Produkte Human Gut Microbiota Metabolites Plants Moraceae Endogenous metabolite Morus alba Linn. Source Classification	Reference Standards Antifolate Endogenous Metabolite
Folinic acid (Standard) is the analytical standard of Folinic acid. This product is intended for research and analytical applications. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity .

HY-16637D

Folic acid disodium Maximum Cited Publications 25 Publications Verification Vitamin B9 disodium; Vitamin M disodium	Natürliche Produkte Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite DNA/RNA Synthesis
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-129398

Formiminoglutamic acid	Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Formiminoglutamic acid, an endogenous metabolite, could be an index of folic-acid deficiency .

HY-137129

10-Formyl-7,8-dihydrofolic acid	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Dihydrofolate reductase (DHFR)
10-Formyl-7,8-dihydrofolic acid is a biologically active folic acid and growth promoter. 10-Formyl-7,8-dihydrofolic acid serves as a substrate for aminoimidazolecarboxamide ribonucleotide transformylase and dihydrofolate reductase (DHFR) to support catalytic reactions (with detection wavelengths of 552 nm and 340 nm, respectively). 10-Formyl-7,8-dihydrofolic acid not only promotes the growth of leukemia cells, but also effectively reverses the growth inhibition induced by antifolate drugs under folate-deficient conditions. 10-Formyl-7,8-dihydrofolic acid can be used in the research of leukemia .

HY-16637A

Folic acid sodium Vitamin B9 sodium; Vitamin M sodium	Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-113046R

5-Methyltetrahydrofolic acid (Standard) 1 Publications Verification 5-Methyl THF (Standard); 5-MTHF (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.

HY-B1008R

4-Aminobenzoic acid (Standard) PABA (Standard); p-Aminobenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
4-Aminobenzoic acid (Standard) is the analytical standard of 4-Aminobenzoic acid. This product is intended for research and analytical applications. 4-Aminobenzoic acid is an intermediate in the synthesis of folic acid by bacteria, plants and fungi.

HY-13664R

Folinic acid calcium (Standard) Leucovorin calcium (Standard); Calcium folinate (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Antifolate Endogenous Metabolite
Folinic acid (calcium) (Standard) is the analytical standard of Folinic acid (calcium). This product is intended for research and analytical applications. Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .

HY-17556A

Folinic acid disodium Leucovorin disodium	Natürliche Produkte Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite Antifolate
Folinic acid (Leucovorin) disodium is a biological folic acid and is a forms of vitamin B9. Folinic acid disodium is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity. Folinic acid disodium and Sfluorouracil adjuvant chemotherapy shows effective in colon carcinoma .

HY-17556B

Folinic acid calcium hydrate Leucovorin calcium hydrate	Natürliche Produkte Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Antifolate Endogenous Metabolite
Folinic acid (Leucovorin) calcium hydrate is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease Methotrexate-induced toxicity .

HY-133668R

Monoethyl phthalate (Standard)	Other disease Disease markers Endogenous metabolite	Drug Metabolite Reference Standards
Sulfamonomethoxine (sodium) (Standard) is the analytical standard of Sulfamonomethoxine (sodium). This product is intended for research and analytical applications. Sulfamonomethoxine sodium is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate .

HY-N16022

N-TETAMINE-pSar45-Folate	Lipid	Biochemical Assay Reagents
N-TETAMINE-pSar45-Folate is a lipid that is composed of a Folic acid (HY-16637) unit conjugated to a N-TETAMINE-pSar45. N-TETAMINE-pSar45-Folate can be used to prepare lipid nanoparticles for drug delivery.

Art. -Nr.	Produktname	Chemical Structure

HY-14519S

Methotrexate-d3

Methotrexate-d₃ (Amethopterin-d₃) is the deuterium labeled Methotrexate. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

HY-16637S1

Folic acid-d4
Folic acid-d₄ is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-14781S1

Levomefolic acid-13C,d3
Levomefolic acid- ¹³C,d₃ is the deuterium labeled Levomefolic acid (HY-14781) . Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-113046S

5-Methyltetrahydrofolic acid-13C5
5-Methyltetrahydrofolic acid- ¹³C₅ is the ¹³C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid .

HY-17556S1

Folinic acid-d4 calcium hydrate
Folinic acid-d₄-1 (Leucovorin-d₄-1) calcium hydrate is deuterated labeled Folinic acid (HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease Methotrexate-induced toxicity.

HY-16637S

Folic acid-d2
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16637S5

Folic acid-13C6
Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-16637S3

Folic acid-13C5
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16637S4

Folic acid-13C5,15N
Folic acid- ¹⁵N, ¹³C₅ is the ¹³C₅ and ¹⁵N labeled Folic acid (HY-16637) .

HY-113046S1

5-Methyltetrahydrofolic acid-13C6

5-Methyltetrahydrofolic acid- ¹³C₆ (5-Methyl THF- ¹³C₆) is ¹³C labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases .

HY-B0946S

Sulfamonomethoxine-d4
Sulfamonomethoxine-d₄ is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-14781S2

Levomefolic acid-13C5
Levomefolic acid- ¹³C₅ is the ¹³C labeled Levomefolic acid . Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-14781S3

Levomefolic acid-d3
Levomefolic acid-d₃ (L-5-MTHF-d₃) is deuterium labeled Levomefolic acid. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements .

HY-18062S

Pyrimethamine-d3
Pyrimethamine-d₃ is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR) .

HY-W653912A

Leucovorin-d4 calcium hydrate, >90%
Leucovorin-d₄ (Leucovorin-d₄) calcium hydrate, >90% is a deuterated labeled Folinic acid (Leucovorin, HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity .

HY-W740790

*N-Acetyl folic* acid-d4**
N-Acetyl folic acid-d₄ is the deuterium labeled N-Acetyl folic acid.

HY-W751746

*Dehydro Folic* Acid 1,5-Dimethyl Ester-13C5**
Dehydro Folic Acid 1,5-Dimethyl Ester- ¹³C₅ is the ¹³C-labeled Dehydro Folic Acid 1,5-Dimethyl Ester.

HY-W751764

*Dehydro Folic* Acid 1,5-Dimethyl Ester-13C5,15N**
Dehydro Folic Acid 1,5-Dimethyl Ester- ¹³C₅, ¹⁵N is the ¹³C- and ¹⁵N-labeled Dehydro Folic Acid 1,5-Dimethyl Ester.

HY-16637S2

*(Rac)-Folic* acid-13C5,15N**
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-108251S

Methotrexate metabolite-d3
Methotrexate metabolite-d₃ is the deuterium labeled Methotrexate metabolite. Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent .

HY-B0946S1

Sulfamonomethoxine-d3
Sulfamonomethoxine-d₃ is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0946S3

Sulfamonomethoxine-d3-1
Sulfamonomethoxine-d₃-1 is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0946S2

Sulfamonomethoxine-13C6
Sulfamonomethoxine- ¹³C₆ is the ¹³C₆ labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-130569S1

7-Hydroxymethotrexate-d3
7-Hydroxymethotrexate-d₃ is the deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .

HY-130569S

7-Hydroxymethotrexate-d3 sodium
7-Hydroxymethotrexate-d₃ (sodium) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .

HY-130569S2

7-Hydroxymethotrexate-d3 ammonium
7-Hydroxymethotrexate-d₃ (ammonium) is the deuterium labeled 7-Hydroxymethotrexate ammonium. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .

HY-W654227

7-Hydroxy methotrexate-d3 ammonium salt
7-Hydroxy methotrexate-d₃ (ammonium salt) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .

HY-14519S1

Methotrexate-d3 diammonium

Methotrexate-d₃ diammonium is the deuterium labeled Methotrexate diammonium. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

HY-B0333S

Sulfamethizole-d4

Sulfamethizole-d₄ is the deuterium labeled Sulfamethizole (HY-B0333). Sulfamethizole is a sulfathiazole antibiotic. Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli-mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli. Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms .

HY-B0333S2

Sulfamethizole-d4-1

Sulfamethizole-d₄-1 is the deuterium labeled Sulfamethizole (HY-B0333). Sulfamethizole is a sulfathiazole antibiotic. Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli-mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli. Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms .

HY-113046S2

5-Methyltetrahydrofolic acid-d4

5-Methyltetrahydrofolic acid-d₄ (5-Methyl THF-d₄) is the deuterium labeled 5-Methyltetrahydrofolic acid (HY-113046). 5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases .

Art. -Nr.	Compare	Produktname	Application	Reactivity	Image

HY-P83677

	Folic acid Antibody acidum Folicum,aminomethopterin, folacin,Folic acid, pteroylglutamic acid, pteroylmonoglutamic acid, vitamin B9,vitamin L,vitamin M,PteGlu,PTGA, FA,VM	ELISA	Species independent
	Folic acid Antibody is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Folic acid.

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Art. -Nr.	Produktname		Classification

HY-W1123936B

DBCO-PEG1000-FA DBCO-PEG1000-Folate		DBCO
DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936C

DBCO-PEG2000-FA DBCO-PEG2000-Folate		DBCO
DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936D

DBCO-PEG3400-FA DBCO-PEG3400-Folate		DBCO
DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936H

DBCO-PEG10000-FA DBCO-PEG10000-Folate		DBCO
DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936E

DBCO-PEG5000-FA DBCO-PEG5000-Folate		DBCO
DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

Art. -Nr.	Produktname		Classification

HY-144009

DSPE-PEG-Folate, MW 3350		Pegylated Lipids
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888

DSPE-PEG2000-Folate DSPE-PEG2000(2000) Folate		Pegylated Lipids
DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems [2].

HY-W440890

DSPE-PEG-Folate, MW 5000		Pegylated Lipids
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)		Polymers
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000		Polymers
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W440888C

DSPE-PEG5000-Folate		Pegylated Lipids
DSPE-PEG5000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

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