583037-91-6
Chemical Structure
Folate-FITC
Synonym(s): EC-17
- CAS No.: 583037-91-6
- Formula:C42H36N10O10S
- Molecular Weight:872.86
IUPAC Name: N2-(4-(((2-amino-4-oxo-4,8-dihydropteridin-6-yl)methyl)amino)benzoyl)-N5-(2-(3-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)thioureido)ethyl)-L-glutamine
InChIKey: LMEBZGHLPGBLSU-PMERELPUSA-N
SMILES: O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC=C(NC(NCCNC(CC[C@@H](C(O)=O)NC(C6=CC=C(C=C6)NCC(N=C78)=CNC7=NC(N)=NC8=O)=O)=O)=S)C=C51
Biological Activity: Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Folate-FITC | 95.29% | Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively. | ||||||||||||||||||||
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- [1]. Tummers QR, et al. Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17. Oncotarget. 2016 May 31;7(22):32144-55. [Content Brief]
- [2]. Patil RA, et al. Fluorescence Labeling of Circulating Tumor Cells with a Folate Receptor-Targeted Molecular Probe for Diffuse In Vivo Flow Cytometry. Mol Imaging Biol. 2020 Oct;22(5):1280-1289. [Content Brief]
Keywords
