1 Result for "

G 4232

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "G 4232" in MCE Product Catalog:

Cat. No.: HY-118874H
Research Areas:  

Cancer

G4232 is an immune-silent BCL2 antisense oligonucleotide that binds to BCL2 mRNA to induce target degradation and inhibit Bcl-2 protein translation. G4232 carries 5'-methylcytosine in its two CpG motifs, which eliminates CpG-mediated immunostimulatory activity and does not cause significant splenomegaly or elevated plasma IL-12 levels in SCID mice. G4232 induces Apoptosis. G4232 inhibits tumor growth in a melanoma xenograft model. G4232 can be used in studies of melanoma and prostate cancer .
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