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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
GABA/benzodiazepine receptor complex
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "GABA/benzodiazepine receptor complex" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: Imidazolyl-4-acetic acid
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W743398
CAS No.: 31868-18-5
Synonyms: CS-386
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Research Areas:
Mexazolam (CS-386) is an orally active benzodiazepine and anxiolytic. Benzodiazepines bind to specific BZD-type receptors on the GABA-chloride complex and potentiate the inhibitory effects of GABA .
Cat. No.: HY-19371
CAS No.: 917393-39-6
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Lorediplon is a binder predicted via molecular docking to bind SYT1 and SYN2, with affinity for both targets, and it forms stable complexes to regulate protein function. Lorediplon is also a non-benzodiazepine compound that modulates the GABA receptor and exhibits differential activity toward the α1 subunit. Lorediplon can be used in Alzheimer's disease research .
Cat. No.: HY-183471
CAS No.: 34966-41-1
Synonyms: SQ 65396
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Research Areas:
Cartazolate (SQ 65396) is a pyrazolopyridine modulator with benzodiazepine receptor agonist activity and cyclic AMP phosphodiesterase inhibitory activity. Cartazolate enhances the affinity of 3H-diazepam for brain-specific binding sites, regulates the GABA/benzodiazepine receptor complex, reversibly increases Na +-independent GABA receptor binding sites, and stimulates the binding of [ 3H]flunitrazepam to cerebellar membranes. Cartazolate restores punishment-suppressed behavior and exhibits anxiolytic properties. Cartazolate is applicable to anxiety-related research .
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GABA-IN-4 (Compound 17) is a N-(indol-3-ylglyoxylyl)benzylamine derivative. GABA-IN-4 exhibits high affinity for the benzodiazepine receptor (BzR) (binding site in GABAA receptor complex) with Ki value of 67 nM. Benzodiazepines are widely used as antianxiety, sedative-hypnotic and anticonvulsant agents .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
