31868-18-5
31868-18-5
Chemical Structure
Mexazolam
Synonym(s): CS-386
- CAS No.: 31868-18-5
- Formula:C18H16Cl2N2O2
- Molecular Weight:363.24
IUPAC Name: 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,7,11b-tetrahydrobenzo[f]oxazolo[3,2-d][1,4]diazepin-6(5H)-one
InChIKey: ANUCDXCTICZJRH-UHFFFAOYSA-N
SMILES: CC1COC2(C3=C(Cl)C=CC=C3)N1CC(NC4=CC=C(C=C24)Cl)=O
Biological Activity: Mexazolam (CS-386) is an orally active benzodiazepine and anxiolytic. Benzodiazepines bind to specific BZD-type receptors on the GABA-chloride complex and potentiate the inhibitory effects of GABA[1][2].
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Mexazolam | Mexazolam (CS-386) is an orally active benzodiazepine and anxiolytic. Benzodiazepines bind to specific BZD-type receptors on the GABA-chloride complex and potentiate the inhibitory effects of GABA. | |||||||||||||||||||||
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References
- [1]. Vaz-Serra A, et al. Mexazolam and alprazolam in the treatment of generalised anxiety disorder: a double-blind, randomised clinical trial[J]. Clinical Drug Investigation, 2001, 21(4): 257-263.
- [2]. Fernandes H, et al. Mexazolam: clinical efficacy and tolerability in the treatment of anxiety. Neurol Ther. 2014;3(1):1-14. Published 2014 Mar 29. [Content Brief]
Keywords
