1 Result for "

GCN2iB (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GCN2iB (Standard)" in MCE Product Catalog:

Cat. No.: HY-112654R
CAS No.: 2183470-12-2
GCN2iB (Standard) is the analytical standard of GCN2iB (HY-112654). This product is intended for research and analytical applications. GCN2iB is an ATP-competitive, selective GCN2 inhibitor with an IC50 of 2.4 nM. GCN2iB inhibits the activation of the GCN2 pathway and upregulates GPX4. GCN2iB enhances the anticancer effect of ASNase against acute lymphoblastic leukemia. GCN2iB increases left ventricular ejection fraction, while reducing fasting blood glucose and myocardial fibrosis. GCN2iB can be used in research related to acute lymphoblastic leukemia, acute myeloid leukemia and diabetic cardiomyopathy .
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