1 Result for "

GLP-1R agonist 30

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GLP-1R agonist 30" in MCE Product Catalog:

Cat. No.: HY-173479
CAS No.: 3108380-54-4
Target:  

GLP Receptor

GLP-1R agonist 30 is a selective and orally active GLP-1R agonist with an EC50 of 0.048 nM. GLP-1R has excellent selectivity, with EC50 greater than 20 μM for GLP-2R, GIPR, and GCPR. GLP-1R agonist significantly increases cAMP-stimulating activity while markedly reducing hERG inhibitory activities. GLP-1R agonist has preferable absorption and excellent β-arrestin pathway selectivity. GLP-1R agonist effectively improves glucose tolerance and promoted insulin secretion in B-hGLP1R knock-in mice [1].
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