1 Result for "

HY-W005629

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HY-W005629" in MCE Product Catalog:

Cat. No.: HY-W005629
CAS No.: 1446-61-3
Research Areas:  

Metabolic Disease Cancer

Leelamine is an orally active pyruvate dehydrogenase kinase (PDK) inhibitor with an IC50 value of 9.5 μM, showing a blood glucose lowering effect in the diabetic mouse. Leelamine is also a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine decreases mitotic activity, prostate-specific antigen expression and induces Apoptosis to cell death in cancer cells .
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