116 Results for "

IFN-β

" in MedChemExpress (MCE) Product Catalog:
Products (116)

116 Results for "IFN-β" in MCE Product Catalog:

60
60 Publications Verification
Cat. No.: HY-50698
CAS No.: 755038-02-9
BI 2536 is a dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively . BI-2536 suppresses IFNB (encoding IFN-β) gene transcription .
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60
60 Publications Verification
Cat. No.: HY-P7044
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Source:  
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42
42 Cited Publications
Cat. No.: HY-100564
CAS No.: 1441190-66-4
Purity:  99.95%
Synonyms: 2'-3'-cyclic GMP-AMP
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm .
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42
42 Cited Publications
Cat. No.: HY-100564A
CAS No.: 2734858-36-5
Purity:  99.63%
Synonyms: 2'-3'-cyclic GMP-AMP sodium
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm .
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31
31 Cited Publications
Cat. No.: HY-P7063
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
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10
10 Cited Publications
Cat. No.: HY-P73130
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IFNB1; IFF; Prev. IFNB; Fibroblast Interferon; IFB; IFN-Beta; Interferon Beta; Interferon-Beta; Interferon Beta 1; Interferon, Beta 1, Fibroblast
Species:  
Source:  
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6
6 Cited Publications
Cat. No.: HY-147124
CAS No.: 2642218-43-5
Purity:  98.21%
Target:  

IFNAR

Research Areas:  

Infection Cancer

RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression .
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6
6 Cited Publications
Cat. No.: HY-P73128
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNB1; IFF; Prev. IFNB; Fibroblast Interferon; IFB; IFN-Beta; Interferon Beta; Interferon-Beta; Interferon Beta 1; Interferon, Beta 1, Fibroblast
Species:  
Source:  
CHO
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4
4 Cited Publications
Cat. No.: HY-P7103A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Rat
Source:  
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3
3 Cited Publications
Cat. No.: HY-103241
CAS No.: 293762-45-5
Purity:  99.10%
Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces 42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response . Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner . Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells .
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3
3 Cited Publications
Cat. No.: HY-P80723
Synonyms: IL6; IFNB2; Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2

Host:  

Rabbit

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human

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2
2 Cited Publications
Cat. No.: HY-N8107
CAS No.: 34446-06-5
Matairesinol monoglucoside is a STING activator. Matairesinol monoglucoside modulates the STING-TBK1-IRF3 signaling axis, promotes STING transcriptional expression, increases TBK1 and IRF3 phosphorylation. Matairesinol monoglucoside induces IFN-α and IFN-β production, reduces HBV DNA, HBsAg, and HBeAg expression. Matairesinol monoglucoside can be used for the research of hepatitis b virus (hbv) infection .
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2
2 Cited Publications
Cat. No.: HY-P7024
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IFNB1; IFF; Prev. IFNB; Fibroblast Interferon; IFB; IFN-Beta; Interferon Beta; Interferon-Beta; Interferon Beta 1; Interferon, Beta 1, Fibroblast
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-P73129
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNB1; IFF; Prev. IFNB; Fibroblast Interferon; IFB; IFN-Beta; Interferon Beta; Interferon-Beta; Interferon Beta 1; Interferon, Beta 1, Fibroblast
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-P7044A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P7044G
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-W011890
CAS No.: 38609-97-1
Research Areas:  

Inflammation/Immunology Cancer

Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer .
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1
1 Cited Publications
Cat. No.: HY-173425
CAS No.: 2912492-05-6
STING-IN-15 is an orally active STING inhibitor, with an IC50 of 116 nM against h-STING and an IC50 of 96.3 nM against m-STING. STING-IN-15 inhibits the STING signaling pathway in cells, reduces the secretion of IFN-β and IP-10, downregulates the expression of ISG15, ISG56 and TNF-α, and suppresses the phosphorylation of TBK1/IRF3. STING-IN-15 alleviates systemic and renal inflammation induced by STING agonists in mice, reduces tissue damage and the expression of interferon pathway genes, and inhibits spontaneous tissue inflammation in mice. STING-IN-15 can be used for the research of acute kidney injury and autoimmune/inflammatory diseases .
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1
1 Cited Publications
Cat. No.: HY-137709A
Research Areas:  

Metabolic Disease

2'2'-cGAMP disodium, a synthetic CDN, binds STING in the immune response, inducing IFN-β. 2'2'-cGAMP disodium binds weaker binding to STING than 2'3'-cGAMP (HY-100564) but stronger than other CDNs .
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1
1 Cited Publications
Cat. No.: HY-P80189A
Synonyms: Interleukin BSF 2; BSF 2; BSF-2; CDF; CTL differentiation factor antibody; HGF; HSF; IFN-beta-2; IFNB2; IL 6; IL-6;

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Mouse, Rat

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