2'2'-cGAMP disodium
Based on 1 publication(s) in Google Scholar
2'2'-cGAMP disodium, a synthetic CDN, binds STING in the immune response, inducing IFN-β. 2'2'-cGAMP disodium binds weaker binding to STING than 2'3'-cGAMP (HY-100564) but stronger than other CDNs.
For research use only. We do not sell to patients.
- Purity: 99.6%
- Formula: C20H22N10Na2O13P2
- Molecular Weight:718.37
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 2'2'-cGAMP disodium
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 718.37
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Formula C20H22N10Na2O13P2
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Color White to off-white
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SMILES
O[C@H]1[C@](O[P](OC[C@@]([C@H]2O)([H])O[C@](N3C4=NC=NC(N)=C4N=C3)([H])[C@]2([H])O5)(O[Na])=O)([H])[C@](O[C@]1([H])CO[P]5(O[Na])=O)([H])N6C(NC(N)=NC7=O)=C7N=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Biol Chem
Dynamic control of bacterial antiphage defense through the CdnG-Cap5 cyclic oligonucleotide-based antiphage pathway in Vibrio cholerae. [Abstract]2025 Dec 6;302(1):111021. PMID: 41360261
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2'2'-cGAMP disodium Related Classifications
HY-137709A Related Classifications
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