38609-97-1
38609-97-1
Chemical Structure
Cridanimod
- CAS No.: 38609-97-1
- Formula:C15H11NO3
- Molecular Weight:253.26
IUPAC Name: 2-(9-oxoacridin-10(9H)-yl)acetic acid
InChIKey: UOMKBIIXHQIERR-UHFFFAOYSA-N
SMILES: O=C(O)CN(C1=C2C=CC=C1)C3=CC=CC=C3C2=O
Biological Activity: Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer[1][2].
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Cridanimod | 99.80% | Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer. | ||||||||||||||||||||
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Cridanimod (Standard) | ≥98% | Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-W011890ACridanimod sodium -
Similarity Score 0.76
HY-W014334Carbazole-9-ethanol -
Similarity Score 0.75
HY-W424831Oxcarbazepine impurity 3 -
Similarity Score 0.73
HY-168685c-Myc ligand 1 -
Similarity Score 0.69
HY-N91471-Hydroxy-N-methylacridone -
Similarity Score 0.67
HY-34887Acridone-4-carboxylic acid -
Similarity Score 0.66
HY-W0143863-Amino-9-ethylcarbazole -
Similarity Score 0.66
HY-W103062R9-Acridinecarboxylic acid monohydrate (Standard) -
Similarity Score 0.66
HY-W0227599-Acridinecarboxylic acid -
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References
- [1]. Xenetic Biosciences Announces FDA Acceptance of Investigational New Drug Application to Initiate Phase 2 Clinical Trial of Virexxa® in Endometrial Cancer. AUGUST 19, 2016
- [2]. Matthew J. Carlson, et al. Cridanimod and progestin therapy in hormone-resistant endometrial cancer. Journal of Clinical Oncology, January 30, 2017.
