2 Results for "

ILT7 monoclonal antibody

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ILT7 monoclonal antibody" in MCE Product Catalog:

Cat. No.: HY-P99226
CAS No.: 2245966-28-1
Synonyms: MEDI7734; VIB7734
Daxdilimab (MEDI7734; VIB7734) is a monoclonal antibody targeting immunoglobulin-like transcript 7 (ILT7) that depletes plasmacytoid dendritic cells and reduces IFN1 production by binding to the plasmacytoid dendritic cell-specific surface molecule ILT7 and recruiting effector natural killer cells. Daxdilimab (MEDI7734; VIB7734) can be used for research on systemic lupus erythematosus, systemic sclerosis, and polymyositis .
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Cat. No.: HY-P99226A
Daxdilimab (FUT8-KO) is an anti-ILT7 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.
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