1 Result for "

IWP-2 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IWP-2 (Standard)" in MCE Product Catalog:

Cat. No.: HY-13912R
CAS No.: 686770-61-6
Research Areas:  

Cancer

IWP-2 (Standard) is the analytical standard of IWP-2 (HY-13912). This product is intended for research and analytical applications. IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ .
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