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Pathways Recommended: Membrane Transporter/Ion Channel
Results for "

Ion exchange

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

5

Biochemical Assay Reagents

2

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N13022
    Humic acid
    1 Publications Verification

    Environmental Pollutants Bacterial SOD Inflammation/Immunology Cancer
    Humic acid is an important component of organic matter in soil and water, and serves as a plant regulator. Humic acid has multiple reactive activities such as surface adsorption, ion exchange, and complexation. Humic acid can enhance pyrene degradation by Mycobacterium NJS-1. Humic acid can inhibit the activity of superoxide dismutase and scavenge hydroxyl radicals. Humic acid is also toxic to CEM cells .
    Humic acid
  • HY-W134327A

    Diethylaminoethyl dextran (MW 500000)

    Biochemical Assay Reagents Others
    DEAE-Dextran (MW 500000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds and modified with diethylaminoethyl (DEAE) groups. DEAE-Dextran is a cationic molecule that can be used as a transfection reagent to deliver nucleic acids such as DNA or RNA into cells. Its positive charge interacts with negatively charged cell membranes, facilitating the uptake of nucleic acids. DEAE-Dextran can also be used as an ion-exchange chromatography resin, allowing the separation and purification of biomolecules based on their charge.
    DEAE-dextran (MW 500000)
  • HY-128067
    5-(N,N-Hexamethylene)-amiloride
    2 Publications Verification

    Hexamethylene amiloride; HMA

    Sodium Channel HIV Apoptosis Infection Cancer
    5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na +/H + exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively .
    5-(N,N-Hexamethylene)-amiloride
  • HY-W105310A

    Nacr

    HDAC Sirtuin CDK Bcl-2 Family Apoptosis Others
    Croconic acid disodium (Nacr) is a lysine crotonylation (Kcr) activator and electroactive material. Croconic acid disodium reduces the expression of HDAC2, HDAC3, SIRT1, and SIRT3, and increases the expression of EP300, CITED1, ACSS2, DPF2, CDYL, MLLT3, and YEATS2. Croconic acid disodium elevates intracellular crotonyl-CoA content and global histone lysine crotonylation levels. Croconic acid disodium promotes the growth of bovine fibroblasts, regulates cell cycle progression, and inhibits bovine fibroblast apoptosis (apoptosis). Croconic acid disodium improves the blastocyst development efficiency of bovine somatic cell nuclear transfer embryos. Croconic acid disodium undergoes reversible lithium intercalation/deintercalation reactions via sodium-lithium ion exchange. Croconic acid disodium is applicable to research related to cell growth promotion .
    Croconic acid disodium
  • HY-W076836

    p-aminobenzaldehyde

    Biochemical Assay Reagents Others
    4-Aminobenzaldehyde (p-aminobenzaldehyde) is a useful synthetic reagent and monomer that can be used to synthesize monoazo dyes and photocurable ion exchange resins. 4-Aminobenzaldehyde is also a corrosion inhibitor of metals .
    4-Aminobenzaldehyde
  • HY-B1549

    Dimethylbenzyllaurylammonium chloride

    Environmental Pollutants Biochemical Assay Reagents Others
    Lauryl benzalkonium chloride (Dimethylbenzyllaurylammonium chloride) is a cationic surfactant .
    Lauryl benzalkonium chloride
  • HY-119572

    Biochemical Assay Reagents Inflammation/Immunology
    Sodium zirconium cyclosilicate is an orally administered, non-absorbed, novel, inorganic microporous zirconium silicate compound, is a highly selective cation exchanger that selectively removes excess K + in vivo. Sodium zirconium cyclosilicate can be used in research of chronic kidney disease (CKD) .
    Sodium zirconium cyclosilicate
  • HY-W042301

    Anion Exchangers Carbonic Anhydrase Endothelin Receptor Cardiovascular Disease
    Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na +/Cl --potassium transporter inhibitor with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl -/NaCO3 - anion exchanger, and increases calcium reabsorption while promoting potassium and magnesium excretion. Xipamide is mainly cleared via the renal pathway and causes a temporary decrease in glomerular filtration rate under specific conditions. Xipamide does not affect Ca 2+ signaling induced by endothelin-1 and other factors, nor does it inhibit various ion cotransport or pump activities in red blood cells. Xipamide can be used in researches related to cardiovascular diseases, hypertension (especially with left ventricular hypertrophy), advanced renal failure, and liver cirrhosis with ascites .
    Xipamide
  • HY-W020249

    Biochemical Assay Reagents Others
    Sodium ionophore X is a neutral ionophore that binds highly selectively to sodium ions (Na +) to form stable complexes. Sodium ionophore X can be used to construct ion-selective chemical sensors (including optical sensors and electrochemical sensors) .
    Sodium ionophore X
  • HY-D0172

    AP 6G; Actiron 43-65; Aliquat 100

    Biochemical Assay Reagents Others
    Tetrabutylammonium bromide is an organic ammonium compound, which is often used in catalytic reactions and separation and purification processes. It has a significant catalytic effect in some organic synthesis reactions, and can be used as a surfactant, stabilizer and antibacterial agent, etc. In addition, in some laboratory studies, this compound has also been used as an ion exchanger, solvent extractant, etc.
    Tetrabutylammonium bromide
  • HY-112961

    JAK Interleukin Related STAT Metabolic Disease
    Patiromer is an orally active, selective and non-absorbable intestinal potassium (K +) polymer binder that reversibly binds potassium ions in exchange for calcium (Ca 2+). Patiromer can rapidly and continuously reduce serum potassium levels, maintain a normal blood potassium state, and reduce serum aldosterone levels. Patiromer also increases fecal potassium excretion. Patiromer is mainly used in the study of hyperkalemia associated with diseases such as chronic kidney disease, diabetes, and heart failure, and is particularly suitable for improving renin-angiotensin-aldosterone system inhibitor (RAASi) therapy .
    Patiromer
  • HY-W015876

    (+)-Leucinol

    Aminopeptidase Others
    L-Leucinol ((+)-Leucinol) is a competitive aminopeptidase inhibitor with a Ki value of 17 μM. As a dietary intake inhibitor, L-Leucinol reduces the basal dietary leucine intake in rats via microinjection into the rat anterior piriform cortex .
    L-Leucinol
  • HY-154912

    Chloride Channel Inflammation/Immunology
    PAT1inh-B01 is a selective SLC26A6 inhibitor. PAT1inh-B01 inhibits PAT1 (a Cl -/HCO3 - exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 blocks fluid absorption in small intestine. PAT1inh-B01 can be used for research of small intestinal hyposecretory disorders .
    PAT1inh-B01
  • HY-W004078

    Endogenous Metabolite Metabolic Disease
    4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be utilized for the study of plant amine biosynthesis .
    4-Hydroxybenzylamine
  • HY-A0236

    Sodium Channel Potassium Channel Calcium Channel Calmodulin Cardiovascular Disease
    Aprindine is an Ib-class anti-arrhythmic agent. Aprindine mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine can also regulate intracellular calcium ion concentration by inhibiting Na +/Ca 2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias .
    Aprindine
  • HY-109560

    Zn-DTPA trisodium

    Biochemical Assay Reagents Others
    Pentetate zinc trisodium (Zn-DTPA trisodium) forms stable chelates with metal ions by exchanging zinc for a metal of greater binding capacity .
    Pentetate zinc trisodium
  • HY-154912A

    Chloride Channel Inflammation/Immunology
    PAT1inh-B01 hydrocholide is a selective SLC26A6 inhibitor. PAT1inh-B01 hydrocholide inhibits PAT1 (a Cl -/HCO3 - exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 hydrocholide blocks fluid absorption in small intestine. PAT1inh-B01 hydrocholide can be used for research of small intestinal hyposecretory disorders .
    PAT1inh-B01 hydrochloride
  • HY-100928

    Calcium Channel Neurological Disease
    YS 035 hydrochloride is a Ca 2+ antagonist on cellular uptake and mitochondrial efflux of calcium ions. YS 035 hydrochloride inhibits Ca 2+ uptake by muscle cells and inhibits Na +/Ca 2+ exchange (Ki=28 µM). YS 035 hydrochloride is a useful tool for research on the mitochondrial Ca 2+ transport .
    YS 035 hydrochloride
  • HY-A0236A

    Sodium Channel Potassium Channel Calcium Channel Calmodulin Cardiovascular Disease
    Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. Aprindine hydrochloride mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine hydrochloride significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine hydrochloride can also regulate intracellular calcium ion concentration by inhibiting Na +/Ca 2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine hydrochloride can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias .
    Aprindine hydrochloride
  • HY-157240

    Biochemical Assay Reagents Others
    CEX Ion-exchange resin is a filler that can be used in cation exchange chromatography (Particle size: 60 μm) .
    CEX Ion-exchange resin
  • HY-157237

    Biochemical Assay Reagents Neurological Disease
    AEX Ion-exchange resin is a commonly used AEX filler, which is a hydrophilic polymethacrylate. Particle size: 60μm.
    AEX Ion-exchange resin
  • HY-W739372A

    Biochemical Assay Reagents Others
    Poly(sodium 4-styrenesulfonate) (MW 70000) is an ion exchange exchange polyelectrolyte .
    Polysodium 4-styrenesulfonate (MW 70000)
  • HY-B2143

    Environmental Pollutants Biochemical Assay Reagents Bacterial Infection
    Montmorillonite is composed of two layers of co-top connected silicon oxygen tetrahedral sheet and one layer of co-edge connected aluminum (magnesium) oxygen (hydroxide) octahedral sheet, which consists of a 2:1 structure containing water of crystal. Montmorillonite can be used for large-scale industrial decontamination and can effectively remove harmful ions in sewage. Montmorillonite can also be used as a carrier of ionic antibacterial agents because of its exchangeable hydrated cations, which can adsorb bacteria .
    Montmorillonite
  • HY-W739372

    Biochemical Assay Reagents
    Poly (sodium 4-styrenesulfonate) is a cation exchange polyelectrolyte used to prepare highly mechanically stable and highly reproducible coatings. During the reduction of graphene oxide, Poly (sodium 4-styrenesulfonate) is used to synthesize polymer-coated graphite nanosheets. Furthermore, the interactions between Poly (sodium 4-styrenesulfonate) and metal ions have been studied, and it has been combined with Nafion for mixed coatings in bismuth film electrodes, showcasing its broad application potential in functional materials and electrochemical research .
    Polysodium 4-styrenesulfonate
  • HY-W739372B

    Biochemical Assay Reagents Others
    Poly(sodium 4-styrenesulfonate) (MW 1000000) is an ion exchange exchange polyelectrolyte .
    Polysodium 4-styrenesulfonate (MW 1000000)
  • HY-157238

    Biochemical Assay Reagents Others
    AEX anion-exchange resin 2 is a AEX commonly used filler and is a strong anion exchange medium, Particle size: ~90μm. AEX anion-exchange resin 2 can be used in Ion exchange chromatography
    AEX Anion-exchange resin 2
  • HY-157241

    Biochemical Assay Reagents Others
    CEX Cation-exchange resin 1 is an ion exchange chromatography resin based on monodisperse polystyrene/divinylbenzene (PS-DVB). The particle size of CEX Cation-exchange resin 1 is 50μm and the ligand is -CH2CH2CH2SO3-. CEX Cation-exchange resin 1 can be used for the separation and purification of antibodies, VLPs, viruses and proteins .
    CEX Cation-exchange resin 1
  • HY-109559

    Ca-DTPA trisodium

    Biochemical Assay Reagents Others
    Pentetate calcium trisodium (Ca-DTPA) forms stable chelates with metal ions by exchanging calcium for a metal of greater binding capacity .
    Pentetate calcium trisodium
  • HY-128067R

    Hexamethylene amiloride (Standard); HMA (Standard)

    Sodium Channel HIV Apoptosis Reference Standards Infection Cancer
    5-(N,N-Hexamethylene)-amiloride (Standard) is the analytical standard of 5-(N,N-Hexamethylene)-amiloride. This product is intended for research and analytical applications. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively .
    5-(N,N-Hexamethylene)-amiloride (Standard)
  • HY-W724290

    AP 6G-d36 bromide; Actiron 43-65-d36 bromide; Aliquat 100-d36 bromide

    Isotope-Labeled Compounds Biochemical Assay Reagents Others
    Tetrabutylammonium-d36 bromide (AP 6G-d36 bromide) is the deuterium labeled Tetrabutylammonium bromide (HY-D0172). Tetrabutylammonium bromide is an organic ammonium compound, which is often used in catalytic reactions and separation and purification processes. It has a significant catalytic effect in some organic synthesis reactions, and can be used as a surfactant, stabilizer and antibacterial agent, etc. In addition, in some laboratory studies, this compound has also been used as an ion exchanger, solvent extractant, etc.
    Tetrabutylammonium-d36 bromide
  • HY-A0236AR

    Reference Standards Sodium Channel Potassium Channel Calcium Channel Calmodulin Cardiovascular Disease
    Aprindine hydrochloride (Standard) is the analytical reference standard of Aprindine hydrochloride (HY-A0236A). This product is used for research and analytical applications. Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. Aprindine hydrochloride mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine hydrochloride significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine hydrochloride can also regulate intracellular calcium ion concentration by inhibiting Na +/Ca 2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine hydrochloride can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias.
    Aprindine hydrochloride (Standard)

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