17141-74-1
Chemical Structure
Sodium zirconium cyclosilicate
- CAS No.: 17141-74-1
- Formula:H6O9Si3.2Na.Zr
- Molecular Weight:371.50
IUPAC Name: 1,3,5,2,4,6-trioxatrisilinane-2,2,4,4,6,6-hexaol, disodium zirconium salt
InChIKey: XXKYCRNZDOKQPM-UHFFFAOYSA-N
SMILES: O[Si]1(O[Si](O)(O[Si](O)(O)O1)O)O.[Na].[Zr].[Na]
Biological Activity: Sodium zirconium cyclosilicate is an orally administered, non-absorbed, novel, inorganic microporous zirconium silicate compound, is a highly selective cation exchanger that selectively removes excess K+ in vivo. Sodium zirconium cyclosilicate can be used in research of chronic kidney disease (CKD)[1][2].
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Sodium zirconium cyclosilicate | 95.0% | Sodium zirconium cyclosilicate is an orally administered, non-absorbed, novel, inorganic microporous zirconium silicate compound, is a highly selective cation exchanger that selectively removes excess K+ in vivo. Sodium zirconium cyclosilicate can be used in research of chronic kidney disease (CKD). | ||||||||||||||||||||
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- [1]. Stavros F, et, al. Characterization of structure and function of ZS-9, a K+ selective ion trap. PLoS One. 2014 Dec 22;9(12):e114686. [Content Brief]
- [2]. Ash SR, et, al. A phase 2 study on the treatment of hyperkalemia in patients with chronic kidney disease suggests that the selective potassium trap, ZS-9, is safe and efficient. Kidney Int. 2015 Aug;88(2):404-11. [Content Brief]
Keywords