1 Result for "

JAK1-IN-21

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JAK1-IN-21" in MCE Product Catalog:

Cat. No.: HY-184592
Target:  

JAK STAT Akt PARP Caspase

Research Areas:  

Cancer

JAK1-IN-21, biotin-conjugated isoxazole derivative, is a JAK1 inhibitor. JAK1-IN-21 directly engages and stabilizes JAK1, reduces the phosphorylation of JAK1, STAT1 and AKT, induces apoptotic marker cleavage (PARP, Caspase-3, Caspase-7) and exhibits broad-spectrum antiproliferative activity against cancer cells. JAK1-IN-21 can be used for the study of liver cancer, prostate cancer, and breast cancer .
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