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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Janus Kinase 2
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Janus Kinase 2" in MCE Product Catalog:
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3
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1 Cited Publications
Cat. No.: HY-P701102
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
E. coli
1
Cat. No.: HY-N2521
CAS No.: 52328-97-9
Synonyms: FLLL31
Cat. No.: HY-177131
CAS No.: 2574524-67-5
Target:
Research Areas:
Soficitinib (Compound 20) is a selective tyrosine kinase 2 (TYK2) and Janus kinase 2 (JAK2) inhibitor, with IC50 values of 0.5 nM and 1.2 nM, respectively. Soficitinib shows promise for research into autoimmune diseases (such as psoriasis, rheumatoid arthritis) and inflammatory diseases .
Target:
Research Areas:
Tubulin/JAK2-IN-1 (compound 7g) is a dual inhibitor of Janus kinase 2 (JAK2) and microtubule. Tubulin/JAK2-IN-1 has potent antiproliferative activity against the cancer cells .
Cat. No.: HY-P704597
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706033
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706061
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705808
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P706060
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705709
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706062
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: JAK2; JAK-2; Janus Kinase 2; Janus Kinase 2 (A Protein Tyrosine Kinase); JTK10; Tyrosine-Protein Kinase; Tyrosine-Protein Kinase JAK2; Janus Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P80727A
Synonyms: JAK2; Tyrosine-protein Kinase JAK2; Janus Kinase 2; JAK-2
Cat. No.: HY-E70835
Janus kinase 2 (JAK2) initiates signaling from several cytokine receptors and is required for biological responses such as erythropoiesis. JAK2 contains the kinase (JH1) and pseudokinase domains (JH2). JAK2(JH1/JH2) Recombinant Human Active Protein Kinase is a recombinant JAK2(JH1/JH2) protein that can be used to study JAK2(JH1/JH2)-related functions .
Cat. No.: HY-183670
CAS No.: 3038340-43-8
JAK2-IN-21 is a Janus kinase 2 (JAK2) inhibitor with an IC50 of 12.25 nM. JAK2-IN-21 inhibits the JAK2/STAT3/STAT5 tumor-promoting signaling pathway and reduces JAK2 protein expression. JAK2-IN-21 exhibits selective cytotoxicity against HPV-positive cancer cells and induces cancer cell apoptosis. JAK2-IN-21 can be used in the research of HPV-positive cervical cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
