1 Result for "

KRASG12D-driven tumors

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRASG12D-driven tumors" in MCE Product Catalog:

Cat. No.: HY-176134
CAS No.: 3030493-05-8
Target:  

PROTACs Ras

Research Areas:  

Cancer

RP03707 is a PROTAC degrader of KRAS G12D. RP03707 forms a ternary complex with KRAS G12D and the CRBN E3 ligase, promoting the ubiquitination and proteasomal degradation of KRAS G12D. RP03707 inhibits the growth of KRAS G12D-positive tumor cells .
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