1 Result for "

KRIT1-Rap1-HEG1 ternary complex

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRIT1-Rap1-HEG1 ternary complex" in MCE Product Catalog:

Cat. No.: HY-187330
Target:  

Drug Derivative

Research Areas:  

Cancer

Anticancer agent 356 is a phthaloyl derivative with anticancer activity. Molecular docking results of Anticancer agent 356 show that it binds to the EGFR tyrosine kinase domain, KRIT1-Rap1-HEG1 ternary complex and EF-Pyl-GMPPNP complex, thereby stabilizing the complexes and reducing the flexibility of residues at the binding sites. Anticancer agent 356 exhibits cytotoxicity against prostate cancer cells and breast cancer cells. Anticancer agent 356 can be used in the research of prostate cancer and breast cancer .
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