1 Result for "

KT-333 ammonium

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KT-333 ammonium" in MCE Product Catalog:

Cat. No.: HY-156730A
CAS No.: 2839758-34-6
Target:  

Molecular Glues STAT

Research Areas:  

Cancer

KT-333 ammonium (Compound A) is a molecular glues that degrades STAT3 protein. KT-333 ammonium mediates the selective degradation of STAT3 through the ubiquitin-proteasome system by binding to STAT3 protein and E3 ubiquitin ligase von Hippel-Lindau protein (VHL). KT-333 ammonium has strong selectivity for STAT3 protein degradation and good antitumor activity. KT-333 ammonium can be used in the study of hematologic malignancies such as large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) .
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