1 Result for "

LADW

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LADW" in MCE Product Catalog:

LADW
LADW
0 Images
Cat. No.: HY-P11904
Target:  

Angiotensin-converting Enzyme (ACE) Glycosidase

Research Areas:  

Cardiovascular Disease Metabolic Disease Inflammation/Immunology

LADW is a tetrapeptide derived from the hydrolysate of tuna skeletal muscle myosin, with dual inhibitory activities against angiotensin-converting enzyme 1 (ACE1) and α-glucosidase. The IC50 value of LADW against ACE1 is 28.02 μM, while its IC50 value against Saccharomyces cerevisiae α-glucosidase is 4.40 mM. LADW binds competitively to the active site of ACE1, stabilizes the enzyme conformation, and blocks substrate binding. LADW binds to α-glucosidase to inhibit carbohydrate hydrolysis and can also alter starch structure. LADW can be used in studies related to hypertension and diabetes .
loading...
    loading...
View All Sizes
Assay Types