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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
LAL
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "LAL" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. Lalistat 2 is commonly used to investigate the cell-specific functions of LAL and LAL deficiency in vitro, as well as specifically measure LAL activity in human blood samples or cells .
2
2 Cited Publications
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Lalistat 1 is a potent, selective, and competitive inhibitor of lysosomal acid lipase (LAL) and against purified human LAL (phLAL) with an IC50 of 68 nM. Lalistat 1 is a inhibitor of immunoglobulin A1 protease (IgA1P) proteases for H. influenzae, has less effects on other serine hydrolases (trypsin or β-lactamase, etc.). Lalistat 1 can be used for the research of niemann-pick type C (NPC) disease .
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JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL) .
Cat. No.: HY-RS17291
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Lipa Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lipa gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07684
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Research Areas:
LIPA Human Pre-designed siRNA Set A contains three designed siRNAs for LIPA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23746
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Lipa Rat Pre-designed siRNA Set A contains three designed siRNAs for Lipa gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P85252A
Synonyms: LIPA; Lysosomal acid lipase/cholesteryl ester hydrolase; Acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; Sterol esterase
Cat. No.: HY-RS25072
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Cpq Rat Pre-designed siRNA Set A contains three designed siRNAs for Cpq gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101457R
CAS No.: 1672691-74-5
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JZP-430 (Standard) is the analytical standard of JZP-430 (HY-101457). This product is intended for research and analytical applications. JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL) .
Cat. No.: HY-P703648
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIPA; Triacylglycerol Ester Hydrolase; Lipase A, Lysosomal Acid Type; Triacylglycerol Lipase; LAL; Lysosomal Acid Lipase; Sterol Esterase; Diacylglycerol Lipase; CESD; Cholesteryl Esterase; Lysosomal Acid Lipase/Cholesteryl Ester Hydrolase; Cholesterol Es
Species:
Human
Source:
P. pastoris
Cat. No.: HY-49637
CAS No.: 2909471-62-9
Target:
Research Areas:
Biotin-PEG6-PO (F)-C16 is an activity-based proteomics probe .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
