501104-16-1
Chemical Structure
Lalistat 1
- CAS No.: 501104-16-1
- Formula:C12H18N4O3S
- Molecular Weight:298.37
IUPAC Name: 4-(piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate
InChIKey: XAWUWPUYJUOUOF-UHFFFAOYSA-N
SMILES: O=C(N1CCOCC1)OC2=NSN=C2N3CCCCC3
Biological Activity: Lalistat 1 is a potent, selective, and competitive inhibitor of lysosomal acid lipase (LAL) and against purified human LAL (phLAL) with an IC50 of 68 nM. Lalistat 1 is a inhibitor of immunoglobulin A1 protease (IgA1P) proteases for H. influenzae, has less effects on other serine hydrolases (trypsin or β-lactamase, etc.). Lalistat 1 can be used for the research of niemann-pick type C (NPC) disease[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Lalistat 1 | 99.75% | Lalistat 1 is a potent, selective, and competitive inhibitor of lysosomal acid lipase (LAL) and against purified human LAL (phLAL) with an IC50 of 68 nM. Lalistat 1 is a inhibitor of immunoglobulin A1 protease (IgA1P) proteases for H. influenzae, has less effects on other serine hydrolases (trypsin or β-lactamase, etc.). Lalistat 1 can be used for the research of niemann-pick type C (NPC) disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
