1672691-74-5
1672691-74-5
Chemical Structure
JZP-430
- CAS No.: 1672691-74-5
- Formula:C16H26N4O3S
- Molecular Weight:354.47
IUPAC Name: 4-morpholino-1,2,5-thiadiazol-3-yl cyclooctyl(methyl)carbamate
InChIKey: WKSHMJCYWFOADB-UHFFFAOYSA-N
SMILES: O=C(OC1=NSN=C1N2CCOCC2)N(C3CCCCCCC3)C
Biological Activity: JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
JZP-430 | 99.74% | JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
JZP-430 (Standard) | ≥98% | JZP-430 (Standard) is the analytical standard of JZP-430 (HY-101457). This product is intended for research and analytical applications. JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.74
HY-116815Lalistat 1 -
Similarity Score 0.72
HY-128144Lalistat 2 -
Similarity Score 0.66
HY-152152JZP-MA-13 -
Similarity Score 0.62
HY-152148JZP-MA-11 -
Similarity Score 0.60
HY-17494Timolol -
Similarity Score 0.51
HY-102032AR(RS)-Butyryltimolol (Standard) -
Similarity Score 0.51
HY-102032RButyryltimolol (Standard) -
Similarity Score 0.51
HY-W150930mTOR ligand 1 -
Similarity Score 0.51
HY-17380(S)-Timolol maleate -
Explore the MedChemAI to find more analogs
