1 Result for "

Laduviglusib monohydrochloride (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Laduviglusib monohydrochloride (Standard)" in MCE Product Catalog:

Cat. No.: HY-10182AR
CAS No.: 1797989-42-4
Synonyms: CHIR-99021 monohydrochloride (Standard); CT99021 monohydrochloride (Standard)
Research Areas:  

Cancer

Laduviglusib (monohydrochloride) (Standard) is the analytical standard of Laduviglusib (monohydrochloride). This product is intended for research and analytical applications. Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy .
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