1 Result for "

MPMS-VA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MPMS-VA" in MCE Product Catalog:

Cat. No.: HY-189203
Target:  

ADC Linkers

Research Areas:  

Cancer

MPMS-VA is a highly hydrophilic peptide cleavable linker that can be used for the construction of ADCs. MPMS-VA can be cleaved at the Val-Ala site by lysosomal cathepsin B in tumor cells. MPMS-VA can enhance the hydrophilicity of the antibody-drug conjugate linker-payload system. MPMS-VA improves the plasma stability of relevant ADCs and reduces the systemic release of free payload. MPMS-VA can be applied in research related to solid tumors with co-expression of EGFR/HER2, such as lung cancer, breast cancer, gastric cancer, and urothelial carcinoma .
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