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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
NG-nitro-L-arginine
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "NG-nitro-L-arginine" in MCE Product Catalog:
Synonyms: Nω-nitro-L-arginine; L-NOARG; L-NG-nitroarginine
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NG-nitro-L-arginine (Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine) is a nitric oxide synthase (NO Synthase) inhibitor, with a Kd of 15 nM for constitutive NOS from bovine brain and a Ki of 4.4 μM for inducible NOS from mouse macrophages. NG-nitro-L-arginine competitively blocks the synthesis of NO from L-arginine; in addition, it inhibits endothelium-dependent vasodilation, and exhibits effects such as blood pressure elevation, heart rate reduction and vasoconstriction. NG-nitro-L-arginine regulates mitochondrial respiratory efficiency, antioxidant enzyme activity, lipid peroxidation level and tissue lead content in rats. NG-nitro-L-arginine can be used in studies related to cardiovascular diseases .
Cat. No.: HY-P4545
CAS No.: 67482-93-3
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Cat. No.: HY-P4561
CAS No.: 90331-82-1
Cat. No.: HY-P4725
CAS No.: 133233-38-2
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Cat. No.: HY-P4556
CAS No.: 50572-79-7
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Cat. No.: HY-18729B
CAS No.: 141968-19-6
Synonyms: NG-nitro-D-arginine methyl ester
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D-NAME (NG-Nitro-D-arginine methyl ester) is an orally active enantiomer of L-NAME (HY-18729). D-NAME inhibits Nitric oxide synthase activity in myocardium and aorta (Note: D-NAME was once classified as an inactive substance and used as a negative control in nitric oxide synthase inhibition studies), induces increases in systolic blood pressure and mean arterial blood pressure, reduces mesenteric arterial conductance, elevates the ratio of left ventricular weight to body weight, induces myocardial fibrosis, increases the cross-sectional area of aortic wall, enhances mesenteric vasodilation induced by nitrovasodilators, and releases nitric oxide via its guanidino nitro group. D-NAME has no effect on ovalbumin-induced pulmonary eosinophilia in sensitized mice. D-NAME can be used in hypertension-related research .
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