7 Results for "

Niemann-Pick type C1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Niemann-Pick type C1" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-106443
CAS No.: 289893-25-0
Purity:  99.74%
Synonyms: BRX-220 free base
Arimoclomol (BRX-220 free base) is an orally active co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.Arimoclomol can be used for the study of Niemann–Pick disease type C. Arimoclomol can cross the blood-brain barrier and can be used in research on Niemann-Pick disease type C .
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Cat. No.: HY-153830
CAS No.: 4201-62-1
Synonyms: C16 Lactosylceramide (d18:1/16:0)
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0)) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases .
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Cat. No.: HY-W754473
CAS No.: 2517555-53-0
Category:  

Lipids

Lyso-SM-509, a sphingomyelin, is a biomarker for Niemann-Pick disease Type C .
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Cat. No.: HY-W1120833
m-PEG26-NHS ester is a PEG derivative. m-PEG26-NHS ester can be used for the study of Niemann-Pick type C1 disease .
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Cat. No.: HY-P74695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NPC1; Truncated Niemann-Pick C1; NPC Intracellular Cholesterol Transporter 1; Niemann-Pick C1; Niemann-Pick C1 Protein; POGZ; SLC65A1; NPC; Niemann-Pick Disease, type C1
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-153830S
CAS No.: 2097249-92-6
Synonyms: C16 Lactosylceramide (d18:1/16:0)-d3
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0))-d3 is the deuterium labeled LacCer (d18:1/16:0) (HY-153830). LacCer (d18:1/16:0) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. LacCer (d18:1/16:0) is also upregulated in a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder). LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases .
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Cat. No.: HY-P810362
Synonyms: Niemann Pick C1 protein precursor, Niemann Pick disease, type C1, Niemann-Pick C1 protein, NPC, NPC1, NPC1_HUMAN

Host:  

Rabbit

Application:  

WB, ICC/IF, IF-Tissue, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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