45 Results for "

Oseltamivir

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "Oseltamivir" in MCE Product Catalog:

49
49 Cited Publications
Cat. No.: HY-13317
CAS No.: 196618-13-0
Purity:  99.94%
Synonyms: GS 4104
Target:  

Influenza Virus

Research Areas:  

Infection Cancer

Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively .
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76
76 Publications Verification
Cat. No.: HY-13318
CAS No.: 187227-45-8
Purity:  99.50%
Synonyms: GS 4071; Ro 64-0802; Oseltamivir carboxylate
Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses. Oseltamivir acid has an extremely weak ability to penetrate the BBB under normal physiological conditions, but its blood-brain barrier penetration is significantly enhanced under inflammatory conditions .
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76
76 Publications Verification
Cat. No.: HY-13318A
CAS No.: 1415963-60-8
Purity:  94.33%
Synonyms: GS 4071 hydrochloride; Ro 64-0802 hydrochloride; Oseltamivir carboxylate hydrochloride
Target:  

Drug Metabolite

Research Areas:  

Infection

Oseltamivir acid hydrochloride is an active metabolite of the antiviral agent Oseltamivir (HY-13317) ethylester. Oseltamivir acid hydrochloride belongs to baseline toxicants in toxicity ratio analysis .
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49
49 Cited Publications
Cat. No.: HY-17016
CAS No.: 204255-11-8
Synonyms: GS 4104 phosphate
Target:  

Influenza Virus

Research Areas:  

Infection Cancer

Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
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1
1 Cited Publications
Cat. No.: HY-N7922
CAS No.: 91485-02-8
Synonyms: Decarboxyellagic acid
Urolithin M5 (Decarboxyellagic acid) is an orally active influenza virus neuraminidase inhibitor and neuroprotective agent, with IC50 values of 174.8 μM (HK68), 191.5 μM (pdm09), 243.2 μM (WSN) and 257.1 μM (PR8) against four influenza virus neuraminidases, respectively. Urolithin M5 inhibits viral neuraminidase activity, thereby blocking influenza virus replication (including oseltamivir (HY-13317)-resistant strains), protecting infected mammals from death and improving pulmonary edema. Urolithin M5 forms a hydrogen-bond stabilized complex with IGF1R, and binds to MAPK14, AKT1, NFKB1 and EGFR. Urolithin M5 reduces reactive oxygen species production, inhibits neuronal apoptosis, restores mitochondrial transmembrane potential, and promotes neurite outgrowth of damaged neuronal cells. Urolithin M5 can be used in research related to influenza virus infection and Alzheimer's disease .
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Cat. No.: HY-13318S
CAS No.: 1242184-43-5
Purity:  ≥98.0%
Synonyms: GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3
Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid (HY-13318). Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses. Oseltamivir acid has an extremely weak ability to penetrate the BBB under normal physiological conditions, but its blood-brain barrier penetration is significantly enhanced under inflammatory conditions .
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Cat. No.: HY-14818A
CAS No.: 203120-46-1
Purity:  98.57%
Synonyms: CS-8958
Target:  

Influenza Virus

Research Areas:  

Infection

Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses .
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Cat. No.: HY-13317S
CAS No.: 1093851-61-6
Purity:  98.61%
Oseltamivir-d3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent .
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Cat. No.: HY-N10686
CAS No.: 61077-78-9
Tanshinone IIA anhydride, present in root extracts of Salvia miltiorrhiza, acts as an inhibitor of human carboxylesterase (CE). Tanshinone IIA anhydride has a Ki value of 1.9 nM against hCE1 and a Ki value of 1.4 nM against hiCE. Tanshinone IIA anhydride forms a stable covalent complex with serine Ser221 at the active site of hCE1, blocking the catalytic cycle of carboxylesterase, and the activity of the inactivated enzyme cannot recover spontaneously. Tanshinone IIA anhydride is applicable in metabolism-related studies .
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Cat. No.: HY-13317R
CAS No.: 196618-13-0
Synonyms: GS 4104 (Standard)
Research Areas:  

Infection

Oseltamivir (Standard) is the analytical standard of Oseltamivir. This product is intended for research and analytical applications. Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively .
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Cat. No.: HY-172515
CAS No.: 1035895-88-5
Research Areas:  

Infection

ent-Oseltamivir, the enantiomer of Oseltamivir (HY-13317), is a neuraminidase (NA) of influenza virus inhibitor. ent-Oseltamivir is promising for research of influenza virus infections .
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Cat. No.: HY-147331
CAS No.: 208720-71-2
Research Areas:  

Neurological Disease

Oseltamivir acid methyl ester is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid by carboxylesterase 1 (CES1) .
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Cat. No.: HY-Z1483
CAS No.: 1346604-18-9
Target:  

Drug Intermediate

Research Areas:  

Others

Ethyl 4-acetamido-3-hydroxybenzoate is an Oseltamivir (HY-13317) impurity.
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Cat. No.: HY-131069A
CAS No.: 1438272-42-4
Purity:  99.90%
Target:  

Influenza Virus

Research Areas:  

Infection

MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains .
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Cat. No.: HY-13318R
CAS No.: 187227-45-8
Synonyms: GS 4071 (Standard); Ro 64-0802 (Standard); Oseltamivir carboxylate (Standard)
Oseltamivir acid (Standard) is the analytical standard of Oseltamivir acid. This product is intended for research and analytical applications. Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses .
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Cat. No.: HY-17016R
CAS No.: 204255-11-8
Synonyms: GS 4104 phosphate (Standard)
Research Areas:  

Infection

Oseltamivir (phosphate) (Standard) is the analytical standard of Oseltamivir (phosphate). This product is intended for research and analytical applications. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
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Cat. No.: HY-Z3896
CAS No.: 956267-10-0
Target:  

Drug Intermediate

Research Areas:  

Others

4-N-Desacetyl-5-N-acetyl oseltamivir is an Oseltamivir (HY-13317) impurity,.
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Cat. No.: HY-147331A
CAS No.: 208720-78-9
Research Areas:  

Neurological Disease

Oseltamivir acid methyl ester hydrochloride is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester hydrochloride is converted to oseltamivir acid by carboxylesterase 1 (CES1) .
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Cat. No.: HY-112543
CAS No.: 443639-96-1
Purity:  99.73%
Target:  

Influenza Virus

Research Areas:  

Infection

S119-8 is a broad spectrum inhibitor of influenza A and B viruses, showing activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus, but does not inhibit a non-influenza virus, vesicular stomatitis nirus (VSV) .
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Cat. No.: HY-43575
CAS No.: 1191921-01-3
Target:  

Influenza Virus

Research Areas:  

Infection

Oseltamivir-acetate is an impurity of Oseltamivir. Oseltamivir is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B .
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