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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
111 Results for "
P388 cells
" in MedChemExpress (MCE) Product Catalog:
Products (111)
111 Results for "P388 cells" in MCE Product Catalog:
24
Category:
Disease Research Antibacterial Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields
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6
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Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1 .
6
6 Cited Publications
Synonyms: CL-216942 dihydrochloride
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Bisantrene dihydrochloride is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene dihydrochloride targets eukaryotic type II topoisomerases. Bisantrene dihydrochloride is a substrate of MDR1 .
3
3 Cited Publications
Cat. No.: HY-N3308
CAS No.: 32383-76-9
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3
Category:
Labiatae Terpenoids Ulex europaeus L. Diterpenoids Plants Disease Research Fields Oxytropis falcata Bunge Cancer
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1
N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells .
1
Category:
Infection Microorganisms Cyclopeptides Disease Research Fields Biological Pesticide Research Agricultural Research
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Cat. No.: HY-18351
CAS No.: 915303-09-2
Synonyms: LMP-400; NSC-724998
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Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Cat. No.: HY-18351A
CAS No.: 1228035-68-4
Synonyms: LMP-400 hydrochloride; NSC-724998 hydrochloride
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Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Cat. No.: HY-P3116
CAS No.: 173046-02-1
Cat. No.: HY-N6955
CAS No.: 757202-08-7
Category:
Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Cancer
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Cat. No.: HY-N10208
CAS No.: 1216840-17-3
Category:
Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism Cancer
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Cat. No.: HY-103653
CAS No.: 251111-15-6
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Research Areas:
CKD-731 is a Fumagillin (HY-B0751) analogue. CKD-731 inhibits the proliferation of calf pulmonary artery endothelial cells (CPAE), lymphoma EL-4 cells and murine leukemia P388D1 cells. CKD-731 exerts the effect of inhibiting MetAP-2 activity and blocking angiogenesis. CKD-731 can be used for the research of anti-angiogenesis-related cancer .
Cat. No.: HY-12458
CAS No.: 118292-36-7
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Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml .
Cat. No.: HY-N1631
CAS No.: 53600-24-1
Synonyms: 1-Hydroxyrutaecarpine
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1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity .
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1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity .
Cat. No.: HY-125037
CAS No.: 1190948-58-3
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Cat. No.: HY-N1655
CAS No.: 873999-88-3
Category:
Flavonoids Phenols Polyphenols Selaginella delicatula (Desv.) Alston Selaginellaceae Plants Disease Research Fields Biflavones Cancer
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Synonyms: 2-Aminoadamantane-2-carboxylic acid
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Research Areas:
Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
Cat. No.: HY-114648
CAS No.: 339300-34-4
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJI-9561 exhibits cytotoxicity and antibacterial activity. AJI-9561 inhibits the proliferation of Jurkat T cells and mouse P388 leukemia cells, with its IC50 being 0.88 and 1.63 μM respectively. AJI-9561 can be used for research on anti-cancer and antibacterial properties .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
