173046-02-1
Chemical Structure
Thiocoraline
- CAS No.: 173046-02-1
- Formula:C48H56N10O12S6
- Molecular Weight:1157.41
InChIKey: UPGGKUQISSWRJJ-ZRBWWFCKSA-N
SMILES: O=C([C@@H](N(C([C@@]1([H])N(C(CNC([C@@H](CSC([C@@H](N(C([C@@](CSSC1)([H])N(C(CNC2=O)=O)C)=O)C)CSC)=O)NC(C3=NC4=C(C=CC=C4)C=C3O)=O)=O)=O)C)=O)C)CSC)SC[C@H]2NC(C5=NC6=C(C=CC=C6)C=C5O)=O
Biological Activity: Thiocoraline is a depsipeptide that can be isolated by marine Micromonospora. Thiocoraline has antitumor activity with IC50s of 0.002, 0.002, 0.01 and 0.002 μg/mL in P388, A549, HT-29 and MEL-28 cells, respectively. Thiocoraline also a strong antimicrobial activity against Gram-positive microorganisms[1].
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Thiocoraline | Thiocoraline is a depsipeptide that can be isolated by marine Micromonospora. Thiocoraline has antitumor activity with IC50s of 0.002, 0.002, 0.01 and 0.002 μg/mL in P388, A549, HT-29 and MEL-28 cells, respectively. Thiocoraline also a strong antimicrobial activity against Gram-positive microorganisms. | |||||||||||||||||||||
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Keywords
