1 Result for "

PC12 and AML12 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PC12 and AML12 cells" in MCE Product Catalog:

Cat. No.: HY-163746
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

BuChE-IN-11 (Compound 3b-1) is an selective BuChE inhibitor with an IC50 of 0.44 μM for hBuChE. BuChE-IN-11 has high blood-brain barrier permeability and exhibits strong antioxidant activity due to its free radical scavenging properties. BuChE-IN-11 interacts with the choline binding site, acetyl binding site, and peripheral anionic site, exhibiting submicromolar BuChE inhibitory activity and preventing β-amyloid (Aβ) self-aggregation. BuChE-IN-11 holds promise for research in the field of Alzheimer's disease .
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